Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1) (C-Term), (AA 898-927) antibody

Details for Product No. ABIN657821
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Antigen
Synonyms nf-atc, nfat2, nfatc, si:ch211-198c22.2, NFATC1, 2210017P03Rik, AI449492, AV076380, NF-ATc, NFAT2, NFATc, Nfatcb, NF-ATC, NF-ATc1, NFAT, NFATmac
Epitope
C-Term, AA 898-927
(11), (11), (11), (7), (5), (4), (4), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(84), (28), (20), (2), (1)
Host
Rabbit
(61), (24), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(66), (32), (17), (11), (10), (4), (3), (2), (1), (1), (1), (1)
Pubmed 1 reference available
Quantity 400 µL
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Catalog No. ABIN657821
291.50 $
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Immunogen This NFATC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 898-927 AA from the C-terminal region of human NFATC1.
Clone RB34041
Isotype Ig
Specificity This NFATC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 897-927 amino acids from the C-terminal region of human NFATC1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name NFATC1
Background The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
Synonyms: Nuclear factor of activated T-cells, cytoplasmic 1,NFATC1,NFAT2, NFATC
Molecular Weight 101243 DA
Gene ID 4772
NCBI Accession NP_765977, NP_765978, NP_765975, NP_006153
Research Area Translation Factors, Phospho-specific antibodies, Protein Modifications, Transcription Factors, Signaling, Cell Structure
Application Notes WB = 1:1000, IHC = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment NFATC1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1) (C-Term), (AA 898-927) antibody NFATC1 Antibody (C-term) (ABIN657821) western blot analysis in NCI-H292 cell line lysates (35 µg/lane). This demonstrates the NFATC1 antibody detected the NFATC1 protein (arrow).
Background publications Davila, Froeling, Tan et al.: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, 2010 (PubMed).

Validation Images
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