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Details for Product No. ABIN657821

Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1) (C-Term), (AA 898-927) antibody

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Antigen
Synonyms NF-ATC, NFAT2, NFATc, NF-ATc, Nfatcb, AI449492, AV076380, 2210017P03Rik, NF-ATc1, NFATmac, NFAT, nf-atc, nfat2, nfatc, si:ch211-198c22.2, NFATC1
Epitope
»Alternatives C-Term, AA 898-927
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 1 reference available
Catalog no. ABIN657821
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This NFATC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 898-927 AA from the C-terminal region of human NFATC1.
Clone RB34041
Isotype Ig
Specificity This NFATC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 897-927 amino acids from the C-terminal region of human NFATC1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name NFATC1
Background The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
Synonyms: Nuclear factor of activated T-cells, cytoplasmic 1,NFATC1,NFAT2, NFATC
Molecular Weight 101243 DA
Gene ID 4772
UniProt NP_765977.1, NP_765978.1, NP_765975.1, NP_006153.2
Research Area Translation Factors, Phospho-specific antibodies, Protein Modifications, Transcription Factors, Signaling, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment NFATC1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Background publications Davila, Froeling, Tan et al.: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, 2010 (PubMed).

Alternatives for antigen "Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1)", type "Antibodies"
Hosts (58), (19), (1)
Reactivities (79), (28), (20), (2), (2), (1)
Applications (62), (31), (14), (10), (8), (5), (4), (3), (2), (2), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (10), (6), (5), (4), (4), (4), (4), (3), (3), (2), (1), (1), (1), (1), (1), (1)
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