NFATC1 antibody (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1) (AA 898-927)

Details for Product anti-NFATC1 Antibody No. ABIN657821, Supplier: Log in to see
Antigen
  • nf-atc
  • nfat2
  • nfatc
  • si:ch211-198c22.2
  • NFATC1
  • 2210017P03Rik
  • AI449492
  • AV076380
  • NF-ATc
  • NFAT2
  • NFATc
  • Nfatcb
  • NF-ATC
  • NF-ATc1
  • NFAT
  • NFATmac
  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
  • NFATC1
  • nfatc1
  • Nfatc1
Alternatives
anti-Human NFATC1 antibody for Immunofluorescence
Epitope
AA 898-927, C-Term
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Reactivity
Human
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Host
Rabbit
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Clonality (Clone)
Polyclonal ()
Conjugate
This NFATC1 antibody is un-conjugated
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Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Options
Supplier
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Immunogen This NFATC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 898-927 AA from the C-terminal region of human NFATC1.
Clone RB34041
Isotype Ig
Specificity This NFATC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 897-927 amino acids from the C-terminal region of human NFATC1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name NFATC1 (NFATC1 Antibody Abstract)
Background The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
Synonyms: Nuclear factor of activated T-cells, cytoplasmic 1,NFATC1,NFAT2, NFATC
Molecular Weight 101243 DA
Gene ID 4772
NCBI Accession NP_765977, NP_765978, NP_765975, NP_006153
Research Area Translation Factors, Phospho-specific antibodies, Protein Modifications, Transcription Factors, Signaling, Cell Structure
Pathways RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment NFATC1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1) (AA 898-927), (C-Term) antibody (ABIN657821) NFATC1 Antibody (C-term) (ABIN657821) western blot analysis in NCI-H292 cell line lys...
Background publications Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, 2010 (PubMed).

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