anti-MKNK2 antibody (MAP Kinase Interacting serine/threonine Kinase 2) (AA 36-64)

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Antigen
Synonyms gprk7, mnk2, GPRK7, MNK2, 2010016G11Rik, Gprk7, Mnk2, mknk2, wu:fb37e05, wz5090
Alternatives
Epitope
AA 36-64, N-Term
(39), (21), (15), (4), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine)
(61), (23), (7), (1), (1), (1), (1)
Host
Rabbit
(69), (8)
Clonality (Clone)
Polyclonal ()
Conjugate
This MKNK2 antibody is un-conjugated
(6), (6), (6), (6), (6), (6)
Application
Western Blotting (WB)
(72), (53), (5), (2), (1), (1), (1)
Pubmed 3 references available
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Quantity 400 μL
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Immunogen This Mouse Mknk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-64 AA from the N-terminal region of mouse Mknk2.
Clone RB34640
Isotype Ig
Specificity This Mouse Mknk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 35-64 amino acids from the N-terminal region of human Mouse Mknk2.
Predicted Reactivity Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name Mknk2 (MKNK2 Antibody Abstract)
Background Mknk2 may play a role in the response to environmental stress and cytokines. Appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap (By similarity).
Synonyms: MAP kinase-interacting serine/threonine-protein kinase 2,Mknk2,Mnk2
Molecular Weight 51633 DA
Gene ID 17347
NCBI Accession NP_067437
UniProt Q8CDB0
Research Area Translation Factors, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Chromatin, Signaling, Cell Structure
Pathways MAPK Signaling
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Mouse Mknk2 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-MKNK2 antibody (MAP Kinase Interacting serine/threonine Kinase 2) (AA 36-64) (ABIN657843) Mouse Mknk2 Antibody (N-term) (ABIN657843) western blot analysis in mouse lung tissue...
Background publications Ueda, Sasaki, Elia et al.: "Combined deficiency for MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) delays tumor development." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 32, pp. 13984-90, 2010 (PubMed).

Furic, Rong, Larsson et al.: "eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 32, pp. 14134-9, 2010 (PubMed).

Joshi, Kaur, Redig et al.: "Type I interferon (IFN)-dependent activation of Mnk1 and its role in the generation of growth inhibitory responses." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 29, pp. 12097-102, 2009 (PubMed).

Catalog No. ABIN657843
$324.50
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