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Nemo-Like Kinase antibody (C-Term)

NLK Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB34651 unconjugated
Catalog No. ABIN657850
  • Target See all Nemo-Like Kinase (NLK) Antibodies
    Nemo-Like Kinase (NLK)
    Binding Specificity
    • 15
    • 15
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 408-436, C-Term
    Reactivity
    • 81
    • 34
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 82
    • 4
    Rabbit
    Clonality
    • 83
    • 3
    Polyclonal
    Conjugate
    • 26
    • 8
    • 7
    • 7
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This Nemo-Like Kinase antibody is un-conjugated
    Application
    • 78
    • 41
    • 26
    • 26
    • 24
    • 16
    • 13
    • 10
    • 10
    • 6
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    B, Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This Mouse Nlk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 408-436 amino acids from the C-terminal region of mouse Nlk.
    Clone
    RB34651
    Isotype
    Ig Fraction
    Top Product
    Discover our top product NLK Primary Antibody
  • Application Notes
    WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Mouse Nlk Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    Expiry Date
    6 months
  • Target
    Nemo-Like Kinase (NLK)
    Alternative Name
    Nlk (NLK Products)
    Synonyms
    Amf antibody, Gpi1 antibody, AI194375 antibody, nlk antibody, nlkb antibody, zgc:111875 antibody, Xnlk antibody, nlk1 antibody, nlk2 antibody, NLK antibody, nemo-like antibody, RGD1561602 antibody, glucose-6-phosphate isomerase antibody, nemo like kinase antibody, nemo-like kinase, type 1 antibody, nemo-like kinase L homeolog antibody, Nemo-Like kinase antibody, nemo-like kinase antibody, Gpi antibody, NLK antibody, Nlk antibody, nlk1 antibody, nlk.L antibody, nlk antibody, nemo-like antibody
    Background
    Role in cell fate determination, required for differentiation of bone marrow stromal cells. Acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor. May suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP. Involved in TGFbeta-mediated mesoderm induction, acting downstream of MAP3K7/TAK1 to phosphorylate STAT3.
    Molecular Weight
    58313
    Gene ID
    100044468, 18099
    NCBI Accession
    NP_032728
    UniProt
    O54949
    Pathways
    Ubiquitin Proteasome Pathway
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