Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1) (AA 18-46), (N-Term) antibody

Details for Product No. ABIN657913
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Antigen
Epitope
AA 18-46, N-Term
(18), (16), (16), (14), (13), (5), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(111), (46), (34), (3), (1), (1), (1)
Host
Rabbit
(82), (16), (16), (4), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(6), (6), (5), (5), (5), (4), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(100), (63), (36), (22), (11), (10), (8), (6), (4), (3), (2), (2), (1)
Pubmed 3 references available
Quantity 400 μL
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Immunogen This HEXIM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 AA from the N-terminal region of human HEXIM1.
Clone RB33760
Isotype Ig
Specificity This HEXIM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 amino acids from the N-terminal region of human HEXIM1.
Predicted Reactivity Cow (Bovine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name HEXIM1 (HEXIM1 Antibody Abstract)
Background Expression of this gene is induced by hexamethylene-bis-acetamide in vascular smooth muscle cells. This gene has no introns.
Synonyms: Protein HEXIM1,10614,CLP1, EDG1, HIS1, MAQ1
Molecular Weight 40623 DA
Gene ID 10614
NCBI Accession NP_006451
UniProt O94992
Research Area Translation Factors, Signaling, Phospho-specific antibodies, Protein Modifications, Transcription Factors, Cell Structure
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.47 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment HEXIM1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1) (AA 18-46), (N-Term) antibody HEXIM1 Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane)....
anti-Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1) (AA 18-46), (N-Term) antibody (2) HEXIM1 Antibody (N-term) western blot analysis in mouse NIH-3T3 cell line lysates (3...
anti-Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1) (AA 18-46), (N-Term) antibody (3) HEXIM1 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin...
Background publications Ogba, Doughman, Chaplin et al.: "HEXIM1 modulates vascular endothelial growth factor expression and function in breast epithelial cells and mammary gland." in: Oncogene, Vol. 29, Issue 25, pp. 3639-49, 2010 (PubMed).

Schönichen, Bigalke, Urbanke et al.: "A flexible bipartite coiled coil structure is required for the interaction of Hexim1 with the P-TEFB subunit cyclin T1." in: Biochemistry, Vol. 49, Issue 14, pp. 3083-91, 2010 (PubMed).

Dow, Liu, Rice: "T-loop phosphorylated Cdk9 localizes to nuclear speckle domains which may serve as sites of active P-TEFb function and exchange between the Brd4 and 7SK/HEXIM1 regulatory complexes." in: Journal of cellular physiology, Vol. 224, Issue 1, pp. 84-93, 2010 (PubMed).

Validation Images
Catalog No. ABIN657913
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