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PDE11A antibody (phosphodiesterase 11A) (AA 34-63)

Details for Product anti-PDE11A Antibody No. ABIN657923, Supplier: Login to see New
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Synonyms si:ch211-222f23.5, pde11a, pde11a1, wu:ft39g12, PDE11A, ppnad2, Pde11a, PPNAD2, 6330414F14Rik, A630086N24Rik, Gm350, PDE11A1
AA 34-63, N-Term
(25), (21), (15), (10), (6), (6), (4), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Human, Mouse (Murine)
(66), (23), (20), (5), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
(50), (20)
Clonality (Clone)
Polyclonal ()
This PDE11A antibody is un-conjugated
(8), (3), (3), (3), (3), (3)
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(59), (41), (27), (18), (12), (6), (6), (6), (2), (1)
Pubmed 1 reference available
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Quantity 400 μL
Shipping to United States ( )
Availability Will be delivered in 2 to 4 Business Days
Immunogen This PDE11A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-63 AA from the N-terminal region of human PDE11A.
Clone RB33858
Isotype Ig
Specificity This PDE11A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-63 amino acids from the N-terminal region of human PDE11A.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name PDE11A (PDE11A Antibody Abstract)
Background The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms: Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A,50940,
Molecular Weight 104752 DA
Gene ID 50940
NCBI Accession NP_001070826, NP_001070664, NP_001070665
UniProt Q9HCR9
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Metabolism, Cell Structure
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment PDE11A Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-PDE11A antibody (phosphodiesterase 11A) (AA 34-63) (ABIN657923) PDE11A Antibody (N-term) (ABIN657923) western blot analysis in mouse stomach tissue l...
Background publications DeWan, Triche, Xu et al.: "PDE11A associations with asthma: results of a genome-wide association scan." in: The Journal of allergy and clinical immunology, Vol. 126, Issue 4, pp. 871-873.e9, 2010 (PubMed).

Catalog No. ABIN657923
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