STAM2 antibody (AA 143-172)

Catalog No. ABIN657963

Product Details anti-STAM2 Antibody

Target: STAM2 (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2))

Binding Specificity: AA 143-172

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAM2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This STAM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-172 amino acids from the Central region of human STAM2.

Clone: RB34085

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: STAM2 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for STAM2

Target: STAM2 (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2))

Alternative Name: STAM2 (STAM2 Products)

Synonyms: Hbp antibody, STAM2A antibody, STAM2B antibody, 1200004O12Rik antibody, 5730456G07Rik antibody, BB145015 antibody, stam2 antibody, MGC52950 antibody, zgc:103628 antibody, signal transducing adaptor molecule 2 antibody, signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 antibody, signal transducing adaptor molecule 2 S homeolog antibody, STAM2 antibody, Stam2 antibody, stam2.S antibody, stam2 antibody

Background: The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation.

Molecular Weight: 58164

Gene ID: 10254

NCBI Accession: NP_005834

UniProt: O75886

Pathways: EGFR Signaling Pathway, EGFR Downregulation