PCSK7 antibody (C-Term)

Catalog No. ABIN657966

Product Details anti-PCSK7 Antibody

Target: PCSK7 (Proprotein Convertase Subtilisin/kexin Type 7 (PCSK7))

Binding Specificity: AA 692-721, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCSK7 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PCSK7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 692-721 amino acids from the C-terminal region of human PCSK7.

Clone: RB34092

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: PCSK7 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for PCSK7

Target: PCSK7 (Proprotein Convertase Subtilisin/kexin Type 7 (PCSK7))

Alternative Name: PCSK7 (PCSK7 Products)

Synonyms: PC7 antibody, PCSK7 antibody, lpc antibody, pc7 antibody, pc8 antibody, spc7 antibody, MGC115258 antibody, wu:fj05c03 antibody, zgc:158336 antibody, LPC antibody, PC8 antibody, SPC7 antibody, AA959856 antibody, proprotein convertase subtilisin/kexin type 7 antibody, proprotein convertase subtilisin/kexin type 7 L homeolog antibody, PCSK7 antibody, pcsk7.L antibody, pcsk7 antibody, Pcsk7 antibody

Background: The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease. It is structurally related to its family members, PACE and PACE4. This protein is concentrated in the trans-Golgi network, associated with the membranes, and is not secreted. It can process proalbumin and is thought to be responsible for the activation of HIV envelope glycoproteins gp160 and gp140. This gene has been implicated in the transcriptional regulation of housekeeping genes. Multiple alternatively spliced transcripts are described for this gene but their full length nature is not yet known. Downstream of this gene's map location at 11q23-q24, nucleotides that match part of this gene's 3' end are duplicated and inverted. A translocation breakpoint associated with lymphoma occurs between this gene and its inverted counterpart.

Molecular Weight: 86247

Gene ID: 9159

NCBI Accession: NP_004707

UniProt: Q16549