AVPR1B antibody (C-Term)

Catalog No. ABIN657971

Product Details anti-AVPR1B Antibody

Target: AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))

Binding Specificity: AA 289-317, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AVPR1B antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This AVPR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 289-317 amino acids from the C-terminal region of human AVPR1B.

Clone: RB34126

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: AVPR1B Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for AVPR1B

Target: AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))

Alternative Name: AVPR1B (AVPR1B Products)

Synonyms: LOC443050 antibody, AVPR1B antibody, si:ch211-125a15.3 antibody, AVPR3 antibody, V3/V1b antibody, VIBR antibody, VPR3 antibody, arginine vasopressin receptor 1B antibody, arginine vasopressin receptor 1Ab antibody, AVPR1B antibody, avpr1ab antibody, Avpr1b antibody

Background: The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known.

Molecular Weight: 46971

Gene ID: 553

NCBI Accession: NP_000698

UniProt: P47901

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones