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IGF1 antibody (Insulin-Like Growth Factor 1) (AA 115-144)

Details for Product anti-IGF1 Antibody No. ABIN658020, Supplier: Log in to see
Antigen
  • C730016P09Rik
  • Igf-1
  • IGF-1
  • IGF-1a
  • IGF-1L
  • Igf-I
  • IGF-I
  • IGF-IB
  • IGF1
  • IGF1A
  • IGFI
  • IGFIA
  • Npt2B
Alternatives
anti-Human IGF1 antibody for ELISA
Epitope
AA 115-144, C-Term
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15
14
13
13
12
6
5
5
4
4
4
3
3
3
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
329
155
128
79
12
10
7
3
3
3
2
1
1
1
Host
Rabbit
179
162
36
8
2
2
1
1
Clonality (Clone)
Polyclonal ()
Conjugate
This IGF1 antibody is un-conjugated
35
13
12
10
6
6
6
6
4
4
4
4
4
4
4
4
4
4
4
2
2
2
2
2
2
2
2
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
233
180
72
66
57
56
51
44
39
28
22
22
19
15
7
6
2
2
2
1
Supplier
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Immunogen This IGF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-144 AA from the C-terminal region of human IGF1.
Clone RB33711
Isotype Ig
Specificity This IGF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 114-144 amino acids from the C-terminal region of human IGF1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name IGF1 (IGF1 Antibody Abstract)
Background The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Several transcript variants encoding different isoforms have been found for this gene.
Synonyms: Insulin-like growth factor I,IGF1,IBP1
Molecular Weight 21841 DA
Gene ID 3479
NCBI Accession NP_001104755, NP_000609
UniProt P01343
Research Area Cell Signaling, Protein Modifications, Cell Cycle, Cell Structure
Pathways RTK Signaling
Application Notes WB = 1:1000, IF = 1:10-50, FACS = 1:10-50, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment IGF1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-IGF1 antibody (Insulin-Like Growth Factor 1) (AA 115-144) (ABIN658020) IGF1 Antibody (C-term) (ABIN658020) western blot analysis in A549 cell line lysates (...
Background publications Li, Yin, Hua, Sun, Luo, Wang, Jiang: "The reciprocal regulation of gamma-synuclein and IGF-I receptor expression creates a circuit that modulates IGF-I signaling." in: The Journal of biological chemistry, Vol. 285, Issue 40, pp. 30480-8, 2010 (PubMed).

Canzian, Cox, Setiawan, Stram, Ziegler, Dossus, Beckmann, Blanché, Barricarte, Berg, Bingham, Buring, Buys, Calle, Chanock, Clavel-Chapelon, DeLancey, Diver, Dorronsoro, Haiman, Hallmans, Hankinson, Hunter, Hüsing, Isaacs, Khaw, Kolonel, Kraft, Le Marchan: "Comprehensive analysis of common genetic variation in 61 genes related to steroid hormone and insulin-like growth factor-I metabolism and breast cancer risk in the NCI breast and prostate cancer cohort consortium." in: Human molecular genetics, Vol. 19, Issue 19, pp. 3873-84, 2010 (PubMed).