Homeodomain Interacting Protein Kinase 4 (HIPK4) (C-Term), (AA 533-562) antibody

Details for Product No. ABIN658042
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Antigen
Epitope
C-Term, AA 533-562
(9), (7), (4), (2), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine)
(35), (15), (9), (1), (1)
Host
Rabbit
(36), (5)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(39), (24), (21), (10), (4), (4), (3), (2)
Pubmed 2 references available
Quantity 400 µL
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Catalog No. ABIN658042
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Immunogen This Mouse Hipk4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 533-562 AA from the C-terminal region of mouse Hipk4.
Clone RB34173
Isotype Ig
Specificity This Mouse Hipk4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 532-562 amino acids from the C-terminal region of human Mouse Hipk4.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name Hipk4
Background Protein kinase that phosphorylates murine TP53 at Ser-9, and thus induces TP53 repression of BIRC5 promoter. It may act as a corepressor of transcription factors (Potential).
Synonyms: Homeodomain-interacting protein kinase 4,Hipk4,Gm162
Molecular Weight 69279 DA
Gene ID 233020
NCBI Accession NP_001028487
UniProt Q3V016
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Chromatin, Signaling, Cell Structure
Application Notes WB = 1:1000, IHC = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Mouse Hipk4 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Homeodomain Interacting Protein Kinase 4 (HIPK4) (C-Term), (AA 533-562) antibody Mouse Hipk4 Antibody (C-term) (ABIN658042) western blot analysis in mouse liver tissue lysates (35 µg/lane). This demonstrates the Hipk4 antibody detected the Hipk4 protein (arrow).
Background publications Zambrowicz, Abuin, Ramirez-Solis et al.: "Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 24, pp. 14109-14, 2003 (PubMed).

Arai, Matsushita, Du et al.: "Novel homeodomain-interacting protein kinase family member, HIPK4, phosphorylates human p53 at serine 9." in: FEBS letters, Vol. 581, Issue 29, pp. 5649-57, 2007 (PubMed).

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