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Homeodomain Interacting Protein Kinase 4 (HIPK4) (C-Term) antibody

Antigen

Homeodomain Interacting Protein Kinase 4 (HIPK4)

Synonyms FLJ32818, Gm162
Binding Site
Alternatives

C-Term

Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Mouse (Murine)

Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), ELISA
2 references available
Certificates ISO 9001:2008
Catalog no. ABIN658042
Quantity 0.1 mg  (0.25 mg/ml)  (Variants)
Price 280.50 $   Plus shipping costs $45.00
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Additional Information

Alternative name Hipk4
Gene ID 233020
UniProt NP_001028487.2, Q3V016
Immunogen This Mouse Hipk4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 532-562 amino acids from the C-terminal region of human Mouse Hipk4.
Isotype Ig
Description Other names: Homeodomain-interacting protein kinase 4,Hipk4,Gm162
Characteristics Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Specificity This Mouse Hipk4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 532-562 amino acids from the C-terminal region of human Mouse Hipk4.
Molecular Weight 69279 DA
Comments

Background: Protein kinase that phosphorylates murine TP53 at Ser-9, and thus induces TP53 repression of BIRC5 promoter. It may act as a corepressor of transcription factors (Potential).

Application Details

Application Notes The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500
Concentration 0.25 mg/ml
Purification Purified
Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage Mouse Hipk4 Antibody (C-term) can be refrigerated at 2-8°,C for up to 6 months. For long term storage, place the at -20°,C.
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Chromatin, Signaling, Cell Structure
Restrictions For Research Use only

Publications

Product Zambrowicz, Abuin, Ramirez-Solis et al.: "Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 24, pp. 14109-14, 2003 (PubMed).

Arai, Matsushita, Du et al.: "Novel homeodomain-interacting protein kinase family member, HIPK4, phosphorylates human p53 at serine 9." in: FEBS letters, Vol. 581, Issue 29, pp. 5649-57, 2007 (PubMed).

Alternatives

Alternatives for antigen "Homeodomain Interacting Protein Kinase 4 (HIPK4)", type "Antibodies"
Hosts Rabbit (30), Mouse (1)
Reactivities Human (14), Mouse (Murine) (2), Rat (Rattus) (2), Cow (Bovine) (1), Dog (Canine) (1)
Applications Immunofluorescence (IF) (16), Western Blotting (WB) (15), ELISA (13), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Dot Blot (DB) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (IHC) (1)
Conjugates Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes C-Term (3), N-Term (2), Internal Region (1)