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MAP3K14 antibody (Mitogen-Activated Protein Kinase Kinase Kinase 14) (AA 652-680)

Details for Product anti-MAP3K14 Antibody No. ABIN658077, Supplier: Login to see New
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Synonyms F23F1.4, F23F1_4, mitogen-activated protein kinase kinase kinase 14, FTDCR1B, HS, HSNIK, NIK, Nik, aly
AA 652-680, C-Term
(17), (15), (13), (8), (4), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Mouse (Murine)
(48), (34), (21)
(61), (2)
Clonality (Clone)
Polyclonal ()
This MAP3K14 antibody is un-conjugated
(5), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Western Blotting (WB)
(49), (30), (14), (11), (5), (2), (1), (1), (1)
Pubmed 4 references available
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Quantity 400 μL
Shipping to United States ( )
Availability Will be delivered in 2 to 4 Business Days
Immunogen This Mouse Map3k14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 652-680 AA from the C-terminal region of mouse Map3k14.
Clone RB34816
Isotype Ig
Specificity This Mouse Map3k14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 651-680 amino acids from the C-terminal region of human Mouse Map3k14.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name Map3k14 (MAP3K14 Antibody Abstract)
Background Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Promotes proteolytic processing of NFKB2/P100, which leads to activation of NF-kappa-B via the non-canonical pathway. Could act in a receptor-selective manner.
Synonyms: Mitogen-activated protein kinase kinase kinase 14,Map3k14,Nik
Molecular Weight 103080 DA
Gene ID 53859
NCBI Accession NP_058592
UniProt Q9WUL6
Research Area Ubiquitin-related antibodies, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Chromatin, Signaling, Cell Structure
Pathways NF-kappaB Signaling, TCR Signaling
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Mouse Map3k14 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-MAP3K14 antibody (Mitogen-Activated Protein Kinase Kinase Kinase 14) (AA 652-680) (ABIN658077) Mouse Map3k14 Antibody (C-term) (ABIN658077) western blot analysis in mouse lung tiss...
Background publications Bhattacharyya, Borthakur, Dudeja et al.: "Lipopolysaccharide-induced activation of NF-κB non-canonical pathway requires BCL10 serine 138 and NIK phosphorylations." in: Experimental cell research, Vol. 316, Issue 19, pp. 3317-27, 2010 (PubMed).

Sanjo, Zajonc, Braden et al.: "Allosteric regulation of the ubiquitin:NIK and ubiquitin:TRAF3 E3 ligases by the lymphotoxin-beta receptor." in: The Journal of biological chemistry, Vol. 285, Issue 22, pp. 17148-55, 2010 (PubMed).

Takeshima, Chamoto, Wakita et al.: "Local radiation therapy inhibits tumor growth through the generation of tumor-specific CTL: its potentiation by combination with Th1 cell therapy." in: Cancer research, Vol. 70, Issue 7, pp. 2697-706, 2010 (PubMed).

Moro, Yamada, Tanabe et al.: "Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells." in: Nature, Vol. 463, Issue 7280, pp. 540-4, 2010 (PubMed).

Catalog No. ABIN658077
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