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MAP3K14 antibody (Mitogen-Activated Protein Kinase Kinase Kinase 14) (AA 652-680)

Details for Product anti-MAP3K14 Antibody No. ABIN658077, Supplier: Log in to see
Antigen
  • F23F1.4
  • F23F1_4
  • mitogen-activated protein kinase kinase kinase 14
  • FTDCR1B
  • HS
  • HSNIK
  • NIK
  • Nik
  • aly
  • mitogen-activated protein kinase kinase kinase 14
  • MAPKKK14
  • MAP3K14
  • Map3k14
Alternatives
anti-Mouse (Murine) MAP3K14 antibody for Western Blotting
Epitope
AA 652-680, C-Term
30
18
15
14
7
5
3
3
2
1
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine)
75
59
36
4
2
2
1
1
1
1
1
Host
Rabbit
88
2
Clonality (Clone)
Polyclonal ()
Conjugate
This MAP3K14 antibody is un-conjugated
5
5
5
4
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
75
33
31
23
20
19
13
2
1
1
Options
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Immunogen This Mouse Map3k14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 652-680 AA from the C-terminal region of mouse Map3k14.
Clone RB34816
Isotype Ig
Specificity This Mouse Map3k14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 651-680 amino acids from the C-terminal region of human Mouse Map3k14.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name Map3k14 (MAP3K14 Antibody Abstract)
Background Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Promotes proteolytic processing of NFKB2/P100, which leads to activation of NF-kappa-B via the non-canonical pathway. Could act in a receptor-selective manner.
Synonyms: Mitogen-activated protein kinase kinase kinase 14,Map3k14,Nik
Molecular Weight 103080 DA
Gene ID 53859
NCBI Accession NP_058592
UniProt Q9WUL6
Research Area Ubiquitin-related antibodies, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Chromatin, Signaling, Cell Structure
Pathways NF-kappaB Signaling, TCR Signaling
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Mouse Map3k14 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-MAP3K14 antibody (Mitogen-Activated Protein Kinase Kinase Kinase 14) (AA 652-680) (ABIN658077) Mouse Map3k14 Antibody (C-term) (ABIN658077) western blot analysis in mouse lung tiss...
Background publications Bhattacharyya, Borthakur, Dudeja, Tobacman: "Lipopolysaccharide-induced activation of NF-κB non-canonical pathway requires BCL10 serine 138 and NIK phosphorylations." in: Experimental cell research, Vol. 316, Issue 19, pp. 3317-27, 2010 (PubMed).

Sanjo, Zajonc, Braden, Norris, Ware: "Allosteric regulation of the ubiquitin:NIK and ubiquitin:TRAF3 E3 ligases by the lymphotoxin-beta receptor." in: The Journal of biological chemistry, Vol. 285, Issue 22, pp. 17148-55, 2010 (PubMed).

Takeshima, Chamoto, Wakita, Ohkuri, Togashi, Shirato, Kitamura, Nishimura: "Local radiation therapy inhibits tumor growth through the generation of tumor-specific CTL: its potentiation by combination with Th1 cell therapy." in: Cancer research, Vol. 70, Issue 7, pp. 2697-706, 2010 (PubMed).

Moro, Yamada, Tanabe, Takeuchi, Ikawa, Kawamoto, Furusawa, Ohtani, Fujii, Koyasu: "Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells." in: Nature, Vol. 463, Issue 7280, pp. 540-4, 2010 (PubMed).