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Details for Product No. ABIN658077

Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14) (C-Term), (AA 652-680) antibody

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Antigen
Synonyms HS, NIK, HSNIK, FTDCR1B, Nik, aly, F23F1.4, F23F1_4, mitogen-activated protein kinase kinase kinase 14
Epitope
»Alternatives C-Term, AA 652-680
Reactivity
»Alternatives Mouse (Murine)
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 4 references available
Catalog no. ABIN658077
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This Mouse Map3k14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 652-680 AA from the C-terminal region of mouse Map3k14.
Clone RB34816
Isotype Ig
Specificity This Mouse Map3k14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 651-680 amino acids from the C-terminal region of human Mouse Map3k14.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name Map3k14
Background Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Promotes proteolytic processing of NFKB2/P100, which leads to activation of NF-kappa-B via the non-canonical pathway. Could act in a receptor-selective manner.
Synonyms: Mitogen-activated protein kinase kinase kinase 14,Map3k14,Nik
Molecular Weight 103080 DA
Gene ID 53859
UniProt NP_058592.1, Q9WUL6
Research Area Ubiquitin-related antibodies, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Chromatin, Signaling, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Mouse Map3k14 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Background publications Moro, Yamada, Tanabe et al.: "Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells." in: Nature, Vol. 463, Issue 7280, pp. 540-4, 2010 (PubMed).

Takeshima, Chamoto, Wakita et al.: "Local radiation therapy inhibits tumor growth through the generation of tumor-specific CTL: its potentiation by combination with Th1 cell therapy." in: Cancer research, Vol. 70, Issue 7, pp. 2697-706, 2010 (PubMed).

Sanjo, Zajonc, Braden et al.: "Allosteric regulation of the ubiquitin:NIK and ubiquitin:TRAF3 E3 ligases by the lymphotoxin-beta receptor." in: The Journal of biological chemistry, Vol. 285, Issue 22, pp. 17148-55, 2010 (PubMed).

Bhattacharyya, Borthakur, Dudeja et al.: "Lipopolysaccharide-induced activation of NF-κB non-canonical pathway requires BCL10 serine 138 and NIK phosphorylations." in: Experimental cell research, Vol. 316, Issue 19, pp. 3317-27, 2010 (PubMed).

Alternatives for antigen "Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14)", type "Antibodies"
Hosts (41), (2)
Reactivities (41), (15), (15), (13), (12), (1)
Applications (33), (10), (9), (6), (4), (2), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (6), (5), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
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