Jumonji Domain Containing 6 (JMJD6) (C-Term), (AA 284-311) antibody

Details for Product No. ABIN658081
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Antigen
Synonyms PSR, Ptdsr, PtdSerR, mKIAA0585, D11Ertd195e, 5730436I23Rik, PTDSR, psr, ptdsr, zfpsr, zgc:66264, PTDSR1, GB15204, jmjd6
Epitope
C-Term, AA 284-311
(14), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(53), (33), (28), (17), (17), (14), (11), (4), (4), (1), (1), (1), (1), (1)
Host
Rabbit
(47), (6)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(42), (19), (14), (9), (8), (5), (1), (1)
Pubmed 4 references available
Catalog no. ABIN658081
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This JMJD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 284-311 AA from the C-terminal region of human JMJD6.
Clone RB34875
Isotype Ig
Specificity This JMJD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-311 amino acids from the C-terminal region of human JMJD6.
Predicted Reactivity Cow (Bovine),Chicken,Fruit Fly (Drosophila melanogaster),Mouse (Murine),Rat (Rattus),Xenopus laevis,Zebrafish
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name JMJD6
Background This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells, however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Synonyms: Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6,JMJD6,KIAA0585, PTDSR
Molecular Weight 46462 DA
Gene ID 23210
UniProt NP_055982.2, Q6NYC1, NP_001074930.1
Research Area Cell Cycle, Transcription Factors, Chromatin, Signaling, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment JMJD6 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Jumonji Domain Containing 6 (JMJD6) (C-Term), (AA 284-311) antibody JMJD6 Antibody (C-term) (ABIN658081) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the JMJD6 antibody detected the JMJD6 protein (arrow).
Background publications Zakharova, Dadsetan, Fomina: "Endogenous Jmjd6 gene product is expressed at the cell surface and regulates phagocytosis in immature monocyte-like activated THP-1 cells." in: Journal of cellular physiology, Vol. 221, Issue 1, pp. 84-91, 2009 (PubMed).

Webby, Wolf, Gromak et al.: "Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing." in: Science (New York, N.Y.), Vol. 325, Issue 5936, pp. 90-3, 2009 (PubMed).

Hong, Zang, White et al.: "Interaction of JMJD6 with single-stranded RNA." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 33, pp. 14568-72, 2010 (PubMed).

Mantri, Krojer, Bagg et al.: "Crystal structure of the 2-oxoglutarate- and Fe(II)-dependent lysyl hydroxylase JMJD6." in: Journal of molecular biology, Vol. 401, Issue 2, pp. 211-22, 2010 (PubMed).

Hosts (47), (6)
Reactivities (53), (33), (28), (17), (17), (14), (11), (4), (4), (1), (1), (1), (1), (1)
Applications (42), (19), (14), (9), (8), (5), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (14), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
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