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UBP46 (C-Term) antibody
Western Blotting (WB), ELISA
|2 references available|
|Quantity||0.1 mg (0.25 mg/ml)|
|Price||280.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|UniProt||NP_001127695.1, P62068, NP_073743.2|
|Immunogen||This UBP46 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 240-269 amino acids from the C-terminal region of human UBP46.|
|Description||Other names: Ubiquitin carboxyl-terminal hydrolase 46,USP46,|
|Characteristics||Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)|
|Specificity||This UBP46 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 240-269 amino acids from the C-terminal region of human UBP46.|
|Molecular Weight||42442 DA|
Background: Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP46 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).
|Application Notes||The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500|
|Buffer||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||UBP46 Antibody (C-term) can be refrigerated at 2-8°,C for up to 6 months. For long term storage, place the at -20°,C.|
|Research Area||Metabolism, Cell Structure|
|Restrictions||For Research Use only|
|UBP46 Antibody (C-term) (ABIN658082) western blot analysis in MDA-MB231 cell line lysates (35ug/lane). This demonstrates the UBP46 antibody detected the UBP46 protein (arrow).|
Puente, Sánchez, Overall et al.: "Human and mouse proteases: a comparative genomic approach." in: Nature reviews. Genetics, Vol. 4, Issue 7, pp. 544-58, 2003 (PubMed).
Kushima, Aleksic, Ito et al.: "Association study of ubiquitin-specific peptidase 46 (USP46) with bipolar disorder and schizophrenia in a Japanese population." in: Journal of human genetics, Vol. 55, Issue 3, pp. 133-6, 2010 (PubMed).