Matrin 3 (MATR3) (N-Term), (AA 157-186) antibody

Details for Product No. ABIN658127
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Antigen
Epitope
N-Term, AA 157-186
(9), (7), (5), (1), (1), (1), (1)
Reactivity
Human
(39), (18), (16), (14), (13), (12), (12), (1)
Host
Rabbit
(32), (8)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(29), (12), (10), (4), (4), (3), (3), (2), (1)
Pubmed 4 references available
Quantity 400 μL
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Catalog No. ABIN658127
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Immunogen This MATR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157-186 AA from the N-terminal region of human MATR3.
Clone RB34112
Isotype Ig
Specificity This MATR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-186 amino acids from the N-terminal region of human MATR3.
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name MATR3
Background This locus encodes a nuclear matrix protein. Mutations at this locus have been associated with distal myopathy 2, which often includes vocal cord and pharyngeal weakness. Alternatively spliced transcript variants, including read-through transcripts with an upstream locus have been described. Related pseuodgenses have been defined on chr1 and chrX.
Synonyms: Matrin-3,MATR3,KIAA0723
Molecular Weight 94623 DA
Gene ID 9782
NCBI Accession NP_954659, NP_001181883
UniProt P43243
Research Area Signaling, Phospho-specific antibodies, Protein Modifications, Chromatin, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.3 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment MATR3 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Matrin 3 (MATR3) (N-Term), (AA 157-186) antibody MATR3 Antibody (N-term) (ABIN658127) western blot analysis in 293 cell line lysates (35 µg/lane). This demonstrates the MATR3 antibody detected the MATR3 protein (arrow).
Background publications Malyavantham, Bhattacharya, Barbeitos et al.: "Identifying functional neighborhoods within the cell nucleus: proximity analysis of early S-phase replicating chromatin domains to sites of transcription, RNA polymerase II, HP1gamma, matrin 3 and SAF-A." in: Journal of cellular biochemistry, Vol. 105, Issue 2, pp. 391-403, 2008 (PubMed).

Graubert, Payton, Shao et al.: "Integrated genomic analysis implicates haploinsufficiency of multiple chromosome 5q31.2 genes in de novo myelodysplastic syndromes pathogenesis." in: PLoS ONE, Vol. 4, Issue 2, pp. e4583, 2009 (PubMed).

Senderek, Garvey, Krieger et al.: "Autosomal-dominant distal myopathy associated with a recurrent missense mutation in the gene encoding the nuclear matrix protein, matrin 3." in: American journal of human genetics, Vol. 84, Issue 4, pp. 511-8, 2009 (PubMed).

Zeitz, Malyavantham, Seifert et al.: "Matrin 3: chromosomal distribution and protein interactions." in: Journal of cellular biochemistry, Vol. 108, Issue 1, pp. 125-33, 2009 (PubMed).

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