Microcephalin 1 (MCPH1) (AA 104-133), (N-Term) antibody

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Synonyms RGD1560642, MGC83773, MCPH1, mct, brit1, MGC148665, BRIT1, MCT, 5430437K10Rik, D030046N04Rik
AA 104-133, N-Term
(24), (15), (12), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1)
(88), (25), (1), (1)
(61), (25), (2)
Clonality (Clone)
Polyclonal ()
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Western Blotting (WB)
(75), (37), (23), (10), (5), (3), (1), (1), (1), (1), (1)
Pubmed 3 references available
Quantity 400 μL
Shipping to United States ( )
Availability Will be delivered in 2 to 4 Business Days
Immunogen This MCPH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-133 AA from the N-terminal region of human MCPH1.
Clone RB34189
Isotype Ig
Specificity This MCPH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-133 amino acids from the N-terminal region of human MCPH1.
Predicted Reactivity Monkey
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name MCPH1 (MCPH1 Antibody Abstract)
Background This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described.
Synonyms: Microcephalin,MCPH1,
Molecular Weight 92877 DA
Gene ID 79648
NCBI Accession NP_001166045, NP_078872
UniProt Q8NEM0
Research Area Protein Modifications, Neurology, Cell Structure, Phospho-specific antibodies
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment MCPH1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Microcephalin 1 (MCPH1) (AA 104-133), (N-Term) antibody (ABIN658137) MCPH1 Antibody (N-term) (ABIN658137) western blot analysis in HL-60 cell line lysates...
Background publications Ruaño, Thompson, Kane et al.: "Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?" in: Pharmacogenomics, Vol. 11, Issue 7, pp. 959-71, 2010 (PubMed).

Wang, Fu, Xie et al.: "Common polymorphisms in ITGA2, PON1 and THBS2 are associated with coronary atherosclerosis in a candidate gene association study of the Chinese Han population." in: Journal of human genetics, Vol. 55, Issue 8, pp. 490-4, 2010 (PubMed).

Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Catalog No. ABIN658137
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