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Details for Product No. ABIN658137

Microcephalin 1 (MCPH1) (N-Term), (AA 104-133) antibody

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Antigen
Synonyms RGD1560642, BRIT1, MCT, 5430437K10Rik, D030046N04Rik, MGC83773, MCPH1, mct, brit1, MGC148665
Epitope
»Alternatives N-Term, AA 104-133
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN658137
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This MCPH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-133 AA from the N-terminal region of human MCPH1.
Clone RB34189
Isotype Ig
Specificity This MCPH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-133 amino acids from the N-terminal region of human MCPH1.
Predicted Reactivity Monkey
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name MCPH1
Background This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described.
Synonyms: Microcephalin,MCPH1,
Molecular Weight 92877 DA
Gene ID 79648
UniProt NP_078872.2, Q8NEM0, NP_001166045.1
Research Area Protein Modifications, Neurology, Cell Structure, Phospho-specific antibodies
Application Notes Recommend dilutions: WB : 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment MCPH1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Background publications Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Wang, Fu, Xie et al.: "Common polymorphisms in ITGA2, PON1 and THBS2 are associated with coronary atherosclerosis in a candidate gene association study of the Chinese Han population." in: Journal of human genetics, Vol. 55, Issue 8, pp. 490-4, 2010 (PubMed).

Ruaño, Thompson, Kane et al.: "Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?" in: Pharmacogenomics, Vol. 11, Issue 7, pp. 959-71, 2010 (PubMed).

Alternatives for antigen "Microcephalin 1 (MCPH1)", type "Antibodies"
Hosts (31), (5), (1)
Reactivities (37), (21), (12)
Applications (27), (18), (11), (10), (3), (1), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (8), (3), (3), (1), (1), (1), (1), (1), (1)
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