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Microcephalin 1 (MCPH1) (N-Term), (AA 104-133) antibody

Details for Product No. ABIN658137
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Antigen
Synonyms RGD1560642, BRIT1, MCT, 5430437K10Rik, D030046N04Rik, MGC83773, MCPH1, mct, brit1, MGC148665
Epitope
N-Term, AA 104-133
(15), (7), (3), (3), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(47), (22), (12)
Host
Rabbit
(41), (5), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(37), (27), (15), (10), (3), (1), (1), (1), (1), (1)
Pubmed 3 references available
Quantity 400 µL
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Availability Will be delivered in 2 to 3 Business Days
Catalog No. ABIN658137
291.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This MCPH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-133 AA from the N-terminal region of human MCPH1.
Clone RB34189
Isotype Ig
Specificity This MCPH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-133 amino acids from the N-terminal region of human MCPH1.
Predicted Reactivity Monkey
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name MCPH1
Background This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described.
Synonyms: Microcephalin,MCPH1,
Molecular Weight 92877 DA
Gene ID 79648
UniProt NP_078872.2, Q8NEM0, NP_001166045.1
Research Area Protein Modifications, Neurology, Cell Structure, Phospho-specific antibodies
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment MCPH1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Microcephalin 1 (MCPH1) (N-Term), (AA 104-133) antibody MCPH1 Antibody (N-term) (ABIN658137) western blot analysis in HL-60 cell line lysates (35 µg/lane). This demonstrates the MCPH1 antibody detected the MCPH1 protein (arrow).
Background publications Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Wang, Fu, Xie et al.: "Common polymorphisms in ITGA2, PON1 and THBS2 are associated with coronary atherosclerosis in a candidate gene association study of the Chinese Han population." in: Journal of human genetics, Vol. 55, Issue 8, pp. 490-4, 2010 (PubMed).

Ruaño, Thompson, Kane et al.: "Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?" in: Pharmacogenomics, Vol. 11, Issue 7, pp. 959-71, 2010 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN658137
291.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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