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Modulator of Apoptosis 1 (MOAP1) (AA 37-65), (N-Term) antibody

Details for Product No. ABIN658152, Supplier: Log in to see
Antigen
  • MOAP1
  • MAP-1
  • PNMA4
  • AA987038
  • Map-1
  • Pnma4
Epitope
AA 37-65, N-Term
15
14
7
7
5
4
3
2
1
Reactivity
Human
51
12
1
Host
Rabbit
45
12
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Western Blotting (WB)
54
24
5
4
3
1
1
1
Supplier
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Immunogen This MOAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 AA from the N-terminal region of human MOAP1.
Clone RB34243
Isotype Ig
Specificity This MOAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-65 amino acids from the N-terminal region of human MOAP1.
Predicted Reactivity Monkey
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name MOAP1 (MOAP1 Antibody Abstract)
Background The protein encoded by this gene was identified by its interaction with apoptosis regulator BAX protein. This protein contains a Bcl-2 homology 3 (BH3)-like motif, which is required for the association with BAX. When overexpressed, this gene has been shown to mediate caspase-dependent apoptosis.
Synonyms: Modulator of apoptosis 1,MOAP1,PNMA4
Molecular Weight 39513 DA
Gene ID 64112
NCBI Accession NP_071434
UniProt Q96BY2
Research Area Apoptosis/Necrosis, Cell Structure
Pathways
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment MOAP1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Modulator of Apoptosis 1 (MOAP1) (AA 37-65), (N-Term) antibody (ABIN658152) MOAP1 Antibody (N-term) (ABIN658152) western blot analysis in 293 cell line lysates (...
Background publications Fu, Sukumaran, Yu: "Inhibition of ubiquitin-mediated degradation of MOAP-1 by apoptotic stimuli promotes Bax function in mitochondria." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 24, pp. 10051-6, 2007 (PubMed).

Vos, Dallol, Eckfeld et al.: "The RASSF1A tumor suppressor activates Bax via MOAP-1." in: The Journal of biological chemistry, Vol. 281, Issue 8, pp. 4557-63, 2006 (PubMed).