Modulator of Apoptosis 1 (MOAP1) (N-Term), (AA 37-65) antibody

Details for Product No. ABIN658152
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Antigen
Epitope
N-Term, AA 37-65
(7), (6), (5), (5), (3), (2), (1), (1)
Reactivity
Human
(34), (10), (1)
Host
Rabbit
(31), (6)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(35), (14), (4), (3), (1), (1), (1), (1), (1)
Pubmed 2 references available
Quantity 400 μL
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Catalog No. ABIN658152
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Immunogen This MOAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 AA from the N-terminal region of human MOAP1.
Clone RB34243
Isotype Ig
Specificity This MOAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-65 amino acids from the N-terminal region of human MOAP1.
Predicted Reactivity Monkey
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name MOAP1
Background The protein encoded by this gene was identified by its interaction with apoptosis regulator BAX protein. This protein contains a Bcl-2 homology 3 (BH3)-like motif, which is required for the association with BAX. When overexpressed, this gene has been shown to mediate caspase-dependent apoptosis.
Synonyms: Modulator of apoptosis 1,MOAP1,PNMA4
Molecular Weight 39513 DA
Gene ID 64112
NCBI Accession NP_071434
UniProt Q96BY2
Research Area Apoptosis/Necrosis, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment MOAP1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Modulator of Apoptosis 1 (MOAP1) (N-Term), (AA 37-65) antibody MOAP1 Antibody (N-term) (ABIN658152) western blot analysis in 293 cell line lysates (35 µg/lane). This demonstrates the MOAP1 antibody detected the MOAP1 protein (arrow).
Background publications Vos, Dallol, Eckfeld et al.: "The RASSF1A tumor suppressor activates Bax via MOAP-1." in: The Journal of biological chemistry, Vol. 281, Issue 8, pp. 4557-63, 2006 (PubMed).

Fu, Sukumaran, Yu: "Inhibition of ubiquitin-mediated degradation of MOAP-1 by apoptotic stimuli promotes Bax function in mitochondria." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 24, pp. 10051-6, 2007 (PubMed).

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