Did you know that you can buy products from over 140 different suppliers from us?

AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (C-Term), (AA 227-256) antibody

Details for Product No. ABIN658196
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms Lobe, Lobel, PRAS40, AI227026, 1110012J22Rik, MGC81452, lobe, pras40, fb34a04, wu:fb34a04
Epitope
C-Term, AA 227-256
(19), (11), (7), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(68), (33), (33), (25), (25), (12)
Host
Rabbit
(59), (10)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(49), (28), (20), (12), (10), (6), (2)
Pubmed 3 references available
Quantity 400 µL
Options
Shipping to United States (Change)
Availability Will be delivered in 2 to 3 Business Days
Catalog No. ABIN658196
291.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This AKT1S1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-256 AA from the C-terminal region of human AKT1S1.
Clone RB34859
Isotype Ig
Specificity This AKT1S1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-256 amino acids from the C-terminal region of human AKT1S1.
Predicted Reactivity Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name AKT1S1
Background AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]).[supplied by OMIM].
Synonyms: Proline-rich AKT1 substrate 1,AKT1S1,PRAS40
Molecular Weight 27383 DA
Gene ID 84335
UniProt NP_115751.2, NP_001092103.1, NP_001092102.1
Research Area Protein Modifications, Cell Structure, Phospho-specific antibodies
Application Notes WB = 1:1000, IHC = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment AKT1S1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (C-Term), (AA 227-256) antibody AKT1S1 Antibody (C-term) (ABIN658196) western blot analysis in Hela cell line lysates (35 µg/lane). This demonstrates the AKT1S1 antibody detected the AKT1S1 protein (arrow).
Background publications Sancak, Thoreen, Peterson et al.: "PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase." in: Molecular cell, Vol. 25, Issue 6, pp. 903-15, 2007 (PubMed).

Wang, Harris, Roth et al.: "PRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding." in: The Journal of biological chemistry, Vol. 282, Issue 27, pp. 20036-44, 2007 (PubMed).

Wang, Harris, Lawrence: "Regulation of proline-rich Akt substrate of 40 kDa (PRAS40) function by mammalian target of rapamycin complex 1 (mTORC1)-mediated phosphorylation." in: The Journal of biological chemistry, Vol. 283, Issue 23, pp. 15619-27, 2008 (PubMed).

Hosts (59), (10)
Reactivities (68), (33), (33), (25), (25), (12)
Applications (49), (28), (20), (12), (10), (6), (2)
Conjugates (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (19), (11), (7), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN658196
291.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
back to top