TEA Domain Family Member 3 (TEAD3) (N-Term) antibody

Antigen: TEA Domain Family Member 3 (TEAD3)

Synonyms: TEF5, TEAD5, TEF-5, DTEF-1, ETFR-1, TEAD-3, Tcf13r2, AW125760, TEAD3

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN658226

Additional Information

Alternative name: TEAD3

Gene ID: 7005

UniProt: Q99594, NP_003205.2

Immunogen: This TEAD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-110 amino acids from the N-terminal region of human TEAD3.

Isotype: Ig

Description: Other names: Transcriptional enhancer factor TEF-5,TEAD3,TEAD5, TEF5

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This TEAD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-110 amino acids from the N-terminal region of human TEAD3.

Molecular Weight: 48676 DA

Comments:

Background: This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is predominantly expressed in the placenta and is involved in the transactivation of the chorionic somatomammotropin-B gene enhancer. Translation of this protein is initiated at a non-AUG (AUA) start codon. [provided by RefSeq].

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: TEAD3 Antibody (N-term) can be refrigerated at 2-8° C for up to 6 months. For long term storage, place the at -20° C.

Research Area: Transcription Factors, Translation Factors, Signaling, Cell Structure

Restrictions: For Research Use only

Images

TEAD3 Antibody (N-term) (ABIN658226) western blot analysis in NCI-H292 cell line lysates (35ug/lane). This demonstrates the TEAD3 antibody detected the TEAD3 protein (arrow).

Publications

Product: Maeda, Mazzulli, Farrance et al.: "Mouse DTEF-1 (ETFR-1, TEF-5) is a transcriptional activator in alpha 1-adrenergic agonist-stimulated cardiac myocytes." in: The Journal of biological chemistry, Vol. 277, Issue 27, pp. 24346-52, 2002 (PubMed).

Mungall, Palmer, Sims et al.: "The DNA sequence and analysis of human chromosome 6." in: Nature, Vol. 425, Issue 6960, pp. 805-11, 2003 (PubMed).

Peng, Huang, Jin et al.: "Transcription enhancer factor-5 and a GATA-like protein determine placental-specific expression of the Type I human 3beta-hydroxysteroid dehydrogenase gene, HSD3B1." in: Molecular endocrinology (Baltimore, Md.), Vol. 18, Issue 8, pp. 2049-60, 2004 (PubMed).

Zhao, Ye, Yu et al.: "TEAD mediates YAP-dependent gene induction and growth control." in: Genes & development, Vol. 22, Issue 14, pp. 1962-71, 2008 (PubMed).

Zhang, Liu, Zha et al.: "TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition." in: The Journal of biological chemistry, Vol. 284, Issue 20, pp. 13355-62, 2009 (PubMed).