Ubiquitin Specific Peptidase 15 (USP15) (N-Term), (AA 254-282) antibody

Details for Product No. ABIN658273
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Antigen
Epitope
N-Term, AA 254-282
(23), (9), (7), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(56), (18), (17), (2), (2), (2)
Host
Rabbit
(46), (7), (2), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB)
(49), (38), (8), (7), (5), (2), (2)
Pubmed 3 references available
Quantity 400 μL
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Catalog No. ABIN658273
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Immunogen This USP15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 254-282 AA from the N-terminal region of human USP15.
Clone RB33962
Isotype Ig
Specificity This USP15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-282 amino acids from the N-terminal region of human USP15.
Predicted Reactivity Cow (Bovine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name USP15
Background Ubiquitin (MIM 191339), a highly conserved protein involved in the regulation of intracellular protein breakdown, cell cycle regulation, and stress response, is released from degraded proteins by disassembly of the polyubiquitin chains. The disassembly process is mediated by ubiquitin-specific proteases (USPs). Also see USP1 (MIM 603478).
Synonyms: Ubiquitin carboxyl-terminal hydrolase 15,USP15,KIAA0529
Molecular Weight 112419 DA
Gene ID 9958
NCBI Accession NP_006304
UniProt Q9Y4E8
Research Area Ubiquitin-related antibodies, Signaling, Phospho-specific antibodies, Protein Modifications, Metabolism, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment USP15 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Ubiquitin Specific Peptidase 15 (USP15) (N-Term), (AA 254-282) antibody USP15 Antibody (N-term) (ABIN658273) western blot analysis in mouse cerebellum tissue lysates (35 µg/lane). This demonstrates the USP15 antibody detected the USP15 protein (arrow).
Background publications Beausoleil, Villén, Gerber et al.: "A probability-based approach for high-throughput protein phosphorylation analysis and site localization." in: Nature biotechnology, Vol. 24, Issue 10, pp. 1285-92, 2006 (PubMed).

Vos, Altreuter, White et al.: "The ubiquitin-specific peptidase USP15 regulates human papillomavirus type 16 E6 protein stability." in: Journal of virology, Vol. 83, Issue 17, pp. 8885-92, 2009 (PubMed).

Huang, Langelotz, Hetfeld-Pechoc et al.: "The COP9 signalosome mediates beta-catenin degradation by deneddylation and blocks adenomatous polyposis coli destruction via USP15." in: Journal of molecular biology, Vol. 391, Issue 4, pp. 691-702, 2009 (PubMed).

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