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SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1) (AA 52-81), (N-Term) antibody

Details for Product No. ABIN658274, Supplier: Log in to see
Antigen
  • SMARCB1
  • BAF47
  • INI1
  • MRD15
  • RDT
  • RTPS1
  • SNF5
  • SNF5L1
  • Sfh1p
  • Snr1
  • hSNFS
  • AU020204
  • Baf47
  • Ini1
  • SNF5/INI1
  • Snf5
  • fc51b01
  • smarcb1
  • wu:fc51b01
Epitope
AA 52-81, N-Term
21
15
8
8
7
6
6
4
4
3
3
3
2
2
2
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
114
38
34
7
5
4
2
2
1
1
1
Host
Rabbit
83
33
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
5
5
5
2
2
2
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
88
49
21
20
13
11
8
5
3
3
2
1
1
1
Supplier
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Immunogen This SMARCB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-81 AA from the N-terminal region of human SMARCB1.
Clone RB34035
Isotype Ig
Specificity This SMARCB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-81 amino acids from the N-terminal region of human SMARCB1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name SMARCB1 (SMARCB1 Antibody Abstract)
Background The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Synonyms: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1,SMARCB1,BAF47, INI1, SNF5L1
Molecular Weight 44141 DA
Gene ID 6598
NCBI Accession NP_003064, NP_001007469
UniProt Q12824
Research Area Translation Factors, Phospho-specific antibodies, Protein Modifications, Cancer, Transcription Factors, Chromatin, Signaling, Neurology, Cell Structure
Pathways
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment SMARCB1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1) (AA 52-81), (N-Term) antibody (ABIN658274) SMARCB1 Antibody (N-term) (ABIN658274) western blot analysis in mouse brain tissue ly...
Background publications Bakshi, Hassan, Pratap et al.: "The human SWI/SNF complex associates with RUNX1 to control transcription of hematopoietic target genes." in: Journal of cellular physiology, Vol. 225, Issue 2, pp. 569-76, 2010 (PubMed).

Kohashi, Oda, Yamamoto et al.: "Reduced expression of SMARCB1/INI1 protein in synovial sarcoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 23, Issue 7, pp. 981-90, 2010 (PubMed).

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