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SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1) (N-Term), (AA 52-81) antibody

Details for Product No. ABIN658274
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Antigen
Epitope
N-Term, AA 52-81
(10), (10), (7), (6), (4), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(70), (24), (22), (14), (13), (2), (2), (2), (2), (1)
Host
Rabbit
(49), (27)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(61), (31), (19), (12), (10), (4), (4), (4), (2), (2), (1), (1)
Pubmed 2 references available
Quantity 400 µL
Options
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Catalog No. ABIN658274
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Immunogen This SMARCB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-81 AA from the N-terminal region of human SMARCB1.
Clone RB34035
Isotype Ig
Specificity This SMARCB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-81 amino acids from the N-terminal region of human SMARCB1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name SMARCB1
Background The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Synonyms: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1,SMARCB1,BAF47, INI1, SNF5L1
Molecular Weight 44141 DA
Gene ID 6598
UniProt NP_001007469.1, NP_003064.2, Q12824
Research Area Translation Factors, Phospho-specific antibodies, Protein Modifications, Cancer, Transcription Factors, Chromatin, Signaling, Neurology, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment SMARCB1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1) (N-Term), (AA 52-81) antibody SMARCB1 Antibody (N-term) (ABIN658274) western blot analysis in mouse brain tissue lysates (35 µg/lane). This demonstrates the SMARCB1 antibody detected the SMARCB1 protein (arrow).
Background publications Kohashi, Oda, Yamamoto et al.: "Reduced expression of SMARCB1/INI1 protein in synovial sarcoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 23, Issue 7, pp. 981-90, 2010 (PubMed).

Bakshi, Hassan, Pratap et al.: "The human SWI/SNF complex associates with RUNX1 to control transcription of hematopoietic target genes." in: Journal of cellular physiology, Vol. 225, Issue 2, pp. 569-76, 2010 (PubMed).

Validation Images
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