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XRN2 antibody (5'-3' Exoribonuclease 2) (AA 48-76)

Details for Product anti-XRN2 Antibody No. ABIN658280, Supplier: Login to see
Antigen
  • zgc:55717
  • wu:fb38g12
  • wu:fj53d06
  • AO090012000503
  • DKFZp459J063
  • AtXRN2
  • EXORIBONUCLEASE 2
  • K16E1.2
  • K16E1_2
  • exoribonuclease 2
Epitope
AA 48-76, N-Term
18
15
3
2
2
1
1
Reactivity
Human
34
7
3
2
2
1
1
Host
Rabbit
34
Clonality (Clone)
Polyclonal ()
Conjugate
This XRN2 antibody is un-conjugated
2
2
2
2
2
2
Application
Western Blotting (WB)
31
20
8
4
2
2
Supplier
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Immunogen This XRN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-76 AA from the N-terminal region of human XRN2.
Clone RB34123
Isotype Ig
Specificity This XRN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 47-76 amino acids from the N-terminal region of human XRN2.
Predicted Reactivity Chicken,Fruit Fly (Drosophila melanogaster),Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name XRN2 (XRN2 Antibody Abstract)
Background This gene shares similarity with the mouse Dhm1 and the yeast dhp1 gene. The yeast gene is involved in homologous recombination and RNA metabolism, such as RNA synthesis and RNA trafficking. Complementation studies show that Dhm1 has a similar function in mouse as dhp1. The function of the human gene has not yet been determined. Transcript variants encoding different isoforms have been noted for this gene, however, their full-length nature is not known.
Synonyms: 5'-3' exoribonuclease 2,XRN2,
Molecular Weight 108582 DA
Gene ID 22803
NCBI Accession NP_036387
UniProt Q9H0D6
Research Area Signaling, Phospho-specific antibodies, Protein Modifications, Transcription Factors, Metabolism, Cell Structure
Pathways
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment XRN2 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-XRN2 antibody (5'-3' Exoribonuclease 2) (AA 48-76) (ABIN658280) XRN2 Antibody (N-term) (ABIN658280) western blot analysis in T47D cell line lysates (...
Background publications Lu, Liu, James et al.: "Genetic variants cis-regulating Xrn2 expression contribute to the risk of spontaneous lung tumor." in: Oncogene, Vol. 29, Issue 7, pp. 1041-9, 2010 (PubMed).