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Details for Product No. ABIN658296

protein ariadne-2 homolog (ARIH2) (C-Term), (AA 445-474) antibody

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Synonyms ARI2, TRIAD1, UIP48, AI843547
»Alternatives C-Term, AA 445-474
»Alternatives Human
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
»Alternatives Un-conjugated
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 5 references available
Catalog no. ABIN658296
Quantity 400 µL
291.50 $   Plus shipping costs $45.00
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Immunogen This ARIH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 445-474 AA from the C-terminal region of human ARIH2.
Clone RB34249
Isotype Ig
Specificity This ARIH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 444-474 amino acids from the C-terminal region of human ARIH2.
Predicted Reactivity Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ARIH2
Background E3 ubiquitin-protein ligase mediating 'Lys-48'-and 'Lys-63'-linked polyubiquitination and subsequent proteasomal degradation of modified proteins. May play a role in myelopoiesis.
Synonyms: E3 ubiquitin-protein ligase ARIH2,ARIH2,ARI2, TRIAD1
Molecular Weight 57819 DA
Gene ID 10425
UniProt NP_006312.1, O95376
Research Area Ubiquitin-related antibodies, Phospho-specific antibodies, Protein Modifications, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment ARIH2 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Background publications Marteijn, van Emst, Erpelinck-Verschueren et al.: "The E3 ubiquitin-protein ligase Triad1 inhibits clonogenic growth of primary myeloid progenitor cells." in: Blood, Vol. 106, Issue 13, pp. 4114-23, 2005 (PubMed).

Stelzl, Worm, Lalowski et al.: "A human protein-protein interaction network: a resource for annotating the proteome." in: Cell, Vol. 122, Issue 6, pp. 957-68, 2005 (PubMed).

Matsuoka, Ballif, Smogorzewska et al.: "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage." in: Science (New York, N.Y.), Vol. 316, Issue 5828, pp. 1160-6, 2007 (PubMed).

Marteijn, van der Meer, van Emst et al.: "Gfi1 ubiquitination and proteasomal degradation is inhibited by the ubiquitin ligase Triad1." in: Blood, Vol. 110, Issue 9, pp. 3128-35, 2007 (PubMed).

Marteijn, van der Meer, Smit et al.: "The ubiquitin ligase Triad1 inhibits myelopoiesis through UbcH7 and Ubc13 interacting domains." in: Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, Vol. 23, Issue 8, pp. 1480-9, 2009 (PubMed).

Alternatives for antigen "protein ariadne-2 homolog (ARIH2)", type "Antibodies"
Hosts (28), (7), (5)
Reactivities (39), (18), (18), (14), (14), (13), (3), (2)
Applications (25), (13), (10), (6), (5), (3), (2), (2), (2)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (6), (5), (2), (2), (1), (1), (1)