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SUMO1/sentrin Specific Peptidase 5 (SENP5) (C-Term), (AA 718-747) antibody

Details for Product No. ABIN658321
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Antigen
Epitope
C-Term, AA 718-747
(17), (7), (6), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(56), (26), (17), (13), (12), (12)
Host
Rabbit
(55), (2)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(4), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(42), (35), (26), (10), (8), (1)
Pubmed 1 reference available
Quantity 400 µL
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Catalog No. ABIN658321
291.50 $
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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This SENP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 718-747 AA from the C-terminal region of human SENP5.
Clone RB34338
Isotype Ig
Specificity This SENP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 717-747 amino acids from the C-terminal region of human SENP5.
Predicted Reactivity Mouse (Murine),Monkey
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name SENP5
Background The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1, MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).
Synonyms: Sentrin-specific protease 5,SENP5,
Molecular Weight 86693 DA
Gene ID 205564
UniProt Q96HI0, NP_689912.2
Research Area Metabolism, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.4 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment SENP5 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-SUMO1/sentrin Specific Peptidase 5 (SENP5) (C-Term), (AA 718-747) antibody SENP5 Antibody (C-term) (ABIN658321) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the SENP5 antibody detected the SENP5 protein (arrow).
Background publications Yun, Wang, Mukhopadhyay et al.: "Nucleolar protein B23/nucleophosmin regulates the vertebrate SUMO pathway through SENP3 and SENP5 proteases." in: The Journal of cell biology, Vol. 183, Issue 4, pp. 589-95, 2008 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN658321
291.50 $
Plus shipping costs $45.00
Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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