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Details for Product No. ABIN658321

SUMO1/sentrin Specific Peptidase 5 (SENP5) (C-Term), (AA 718-747) antibody

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Antigen
Synonyms 6230429P13Rik, A730063F07Rik, AI851888, BB189556, SMT3IP3
Epitope
»Alternatives C-Term, AA 718-747
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN658321
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This SENP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 718-747 AA from the C-terminal region of human SENP5.
Clone RB34338
Isotype Ig
Specificity This SENP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 717-747 amino acids from the C-terminal region of human SENP5.
Predicted Reactivity Mouse (Murine),Monkey
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name SENP5
Background The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1, MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).
Synonyms: Sentrin-specific protease 5,SENP5,
Molecular Weight 86693 DA
Gene ID 205564
UniProt Q96HI0, NP_689912.2
Research Area Metabolism, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.4 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment SENP5 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Background publications Yun, Wang, Mukhopadhyay et al.: "Nucleolar protein B23/nucleophosmin regulates the vertebrate SUMO pathway through SENP3 and SENP5 proteases." in: The Journal of cell biology, Vol. 183, Issue 4, pp. 589-95, 2008 (PubMed).

Alternatives for antigen "SUMO1/sentrin Specific Peptidase 5 (SENP5)", type "Antibodies"
Hosts (37), (2)
Reactivities (38), (24), (18), (13), (12), (12)
Applications (29), (16), (11), (10), (10), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (7), (2), (2), (2), (1), (1), (1), (1), (1)
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