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Kruppel-Like Factor 1 (erythroid) (KLF1) (C-Term), (AA 248-276) antibody

Details for Product No. ABIN658420
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Antigen
Synonyms EKLF, HBFQTL6, INLU, Eklf, Nan, KLF1
Epitope
C-Term, AA 248-276
(8), (7), (6), (5), (2), (2), (2), (1), (1)
Reactivity
Human
(33), (10), (4), (4), (2), (1)
Host
Rabbit
(21), (11), (5)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(33), (22), (4), (3), (3), (3), (2), (2), (1), (1), (1)
Pubmed 2 references available
Quantity 400 µL
Options
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Availability Will be delivered in 2 to 3 Business Days
Catalog No. ABIN658420
291.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This KLF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-276 AA from the C-terminal region of human KLF1.
Clone RB34111
Isotype Ig
Specificity This KLF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 247-276 amino acids from the C-terminal region of human KLF1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name KLF1
Background This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype.
Synonyms: Krueppel-like factor 1,KLF1,EKLF
Molecular Weight 38221 DA
Gene ID 10661
UniProt NP_006554.1, Q13351
Research Area Ubiquitin-related antibodies, Translation Factors, Signaling, Phospho-specific antibodies, Protein Modifications, Transcription Factors, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment KLF1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Kruppel-Like Factor 1 (erythroid) (KLF1) (C-Term), (AA 248-276) antibody KLF1 Antibody (C-term) (ABIN658420) western blot analysis in NCI-H292 cell line lysates (35 µg/lane). This demonstrates the KLF1 antibody detected the KLF1 protein (arrow).
Background publications Zhou, Liu, Sun et al.: "KLF1 regulates BCL11A expression and gamma- to beta-globin gene switching." in: Nature genetics, Vol. 42, Issue 9, pp. 742-4, 2010 (PubMed).

Borg, Papadopoulos, Georgitsi et al.: "Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin." in: Nature genetics, Vol. 42, Issue 9, pp. 801-5, 2010 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN658420
291.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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