RAB11A, Member RAS Oncogene Family (RAB11A) (Center) antibody

Antigen: RAB11A, Member RAS Oncogene Family (RAB11A)

Synonyms: YL8, MGC1490, RAB11, rab11, MGC84419, RAB11A, wu:fi15h09, zgc:103679, MGC133992, yl8, DKFZp469L0820, Rab11a, rab11A

Binding Site: Center

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN658451

Additional Information

Alternative name: RAB11A

Gene ID: 8766

UniProt: NP_004654.1, P62491

Immunogen: This RAB11A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-116 amino acids from the Central region of human RAB11A.

Isotype: Ig

Description: Other names: Ras-related protein Rab-11A,RAB11A,RAB11

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This RAB11A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-116 amino acids from the Central region of human RAB11A.

Molecular Weight: 24394 DA

Comments:

Background: The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. It is associated with both constitutive and regulated secretory pathways, and may be involved in protein transport.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: RAB11A Antibody (Center) can be refrigerated at 2-8° C for up to 6 months. For long term storage, place the at -20° C.

Research Area: Signaling, Cell Structure, Protein Modifications, Chromatin

Restrictions: For Research Use only

Images

RAB11A Antibody (Center) (ABIN658451) western blot analysis in A549 cell line lysates (35ug/lane). This demonstrates the RAB11A antibody detected the RAB11A protein (arrow).

Publications

Product: Knödler, Feng, Zhang et al.: "Coordination of Rab8 and Rab11 in primary ciliogenesis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 14, pp. 6346-51, 2010 (PubMed).

Cayouette, Bousquet, Francoeur et al.: "Involvement of Rab9 and Rab11 in the intracellular trafficking of TRPC6." in: Biochimica et biophysica acta, Vol. 1803, Issue 7, pp. 805-12, 2010 (PubMed).

Bruce, Digard, Stuart: "The Rab11 pathway is required for influenza A virus budding and filament formation." in: Journal of virology, Vol. 84, Issue 12, pp. 5848-59, 2010 (PubMed).

Reid, Mulvaney, Turner et al.: "Interaction of the human prostacyclin receptor with Rab11: characterization of a novel Rab11 binding domain within alpha-helix 8 that is regulated by palmitoylation." in: The Journal of biological chemistry, Vol. 285, Issue 24, pp. 18709-26, 2010 (PubMed).

Husebye, Aune, Stenvik et al.: "The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes." in: Immunity, Vol. 33, Issue 4, pp. 583-96, 2010 (PubMed).