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Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 480-509), (C-Term) antibody

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Synonyms RIPK3, RIP3, 2610528K09Rik, AW107945, Rip3, Hcyp2
AA 480-509, C-Term
(31), (20), (16), (15), (10), (7), (6), (5), (5), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
(117), (41), (17), (7), (6), (4), (2), (1)
(125), (24)
Clonality (Clone)
Polyclonal ()
(9), (7), (5), (5), (5), (5), (1)
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(132), (63), (61), (25), (7), (5), (4), (4), (3), (1), (1), (1)
Pubmed 2 references available
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Quantity 400 μL
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Availability Will be delivered in 2 to 4 Business Days
Immunogen This RIPK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 480-509 AA from the C-terminal region of human RIPK3.
Clone RB34507
Isotype Ig
Specificity This RIPK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 479-509 amino acids from the C-terminal region of human RIPK3.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name RIPK3 (RIPK3 Antibody Abstract)
Background The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
Synonyms: Receptor-interacting serine/threonine-protein kinase 3,RIPK3,RIP3
Molecular Weight 56887 DA
Gene ID 11035
NCBI Accession NP_006862
UniProt Q9Y572
Research Area Apoptosis/Necrosis, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Chromatin, Signaling, Cell Structure
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment RIPK3 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 480-509), (C-Term) antibody (ABIN658475) RIPK3 Antibody (C-term) (ABIN658475) western blot analysis in K562 cell line lysates ...
Background publications Goyenechea, Crujeiras, Abete et al.: "Expression of two inflammation-related genes (RIPK3 and RNF216) in mononuclear cells is associated with weight-loss regain in obese subjects." in: Journal of nutrigenetics and nutrigenomics, Vol. 2, Issue 2, pp. 78-84, 2009 (PubMed).

He, Wang, Miao et al.: "Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha." in: Cell, Vol. 137, Issue 6, pp. 1100-11, 2009 (PubMed).

Catalog No. ABIN658475
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