UBA1 antibody (Ubiquitin-Like Modifier Activating Enzyme 1) (AA 1-30)

Details for Product anti-UBA1 Antibody No. ABIN658476, Supplier: Log in to see
Antigen
  • DDBDRAFT_0190927
  • DDBDRAFT_0220497
  • DDB_0190927
  • DDB_0220497
  • a1s9
  • a1s9t
  • a1st
  • amcx1
  • gxp1
  • poc20
  • smax2
  • uba1a
  • ube1
  • ube1x
  • uba1
  • uba1b
  • ube
  • zgc:66143
  • wu:fa01e08
  • wu:fb30f01
  • wu:fi21c11
  • wu:fj14g11
  • A1S9
  • A1S9T
  • A1ST
  • AMCX1
  • GXP1
  • POC20
  • SMAX2
  • UBA1A
  • UBE1
  • UBE1X
  • Sbx
  • Ube-1
  • Ube1x
  • AA986091
  • Arx
  • Sae2
  • UBA1
  • Ubl1a2
  • Uble1b
  • ubiquitin activating enzyme E1
  • ubiquitin-like modifier activating enzyme 1
  • Ubiquitin-conjugating enzyme E1
  • ubiquitin-like modifier activating enzyme 2
  • uae1
  • uba1-b
  • uba1-a
  • uba1
  • GL50803_4083
  • GL50803_10661
  • UBA1
  • Uba1
  • Uba2
Epitope
AA 1-30, N-Term
16
15
15
2
2
1
1
1
1
1
1
1
Reactivity
Human
66
24
15
4
3
3
3
2
1
1
1
1
1
1
Host
Rabbit
62
4
Clonality (Clone)
Polyclonal ()
Conjugate
This UBA1 antibody is un-conjugated
4
4
4
4
4
4
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
61
40
40
8
6
4
2
1
1
Options
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Immunogen This UBA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 AA from the N-terminal region of human UBA1.
Clone RB34509
Isotype Ig
Specificity This UBA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human UBA1.
Predicted Reactivity Cow (Bovine),Mouse (Murine),Rat (Rattus),Rabbit
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name UBA1 (UBA1 Antibody Abstract)
Background The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described.
Synonyms: Ubiquitin-like modifier-activating enzyme 1,UBA1,A1S9T, UBE1
Molecular Weight 117849 DA
Gene ID 7317
NCBI Accession NP_695012, NP_003325
UniProt P22314
Research Area Ubiquitin-related antibodies, Signaling, Phospho-specific antibodies, Protein Modifications, Chromatin, Neurology, Cell Structure
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment UBA1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-UBA1 antibody (Ubiquitin-Like Modifier Activating Enzyme 1) (AA 1-30) (ABIN658476) UBA1 Antibody (N-term) (ABIN658476) western blot analysis in K562 cell line lysates (...
Background publications Carbia-Nagashima, Gerez, Perez-Castro, Paez-Pereda, Silberstein, Stalla, Holsboer, Arzt: "RSUME, a small RWD-containing protein, enhances SUMO conjugation and stabilizes HIF-1alpha during hypoxia." in: Cell, Vol. 131, Issue 2, pp. 309-23, 2007 (PubMed).

Jin, Li, Gygi, Harper: "Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging." in: Nature, Vol. 447, Issue 7148, pp. 1135-8, 2007 (PubMed).