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Details for Product No. ABIN658476

Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) (N-Term), (AA 1-30) antibody

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Antigen
Synonyms
AA986091, Arx, Sae2, UBA1, Ubl1a2, Uble1b, A1S9, A1S9T, A1ST, AMCX1, GXP1, POC20, SMAX2, UBA1A, UBE1, UBE1X, Sbx, Ube-1, Ube1x, DDBDRAFT_0190927, DDBDRAFT_0220497, DDB_0190927, DDB_0220497, a1s9, a1s9 ... show more
Epitope
»Alternatives N-Term, AA 1-30
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 2 references available
Catalog no. ABIN658476
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This UBA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 AA from the N-terminal region of human UBA1.
Clone RB34509
Isotype Ig
Specificity This UBA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human UBA1.
Predicted Reactivity Cow (Bovine),Mouse (Murine),Rat (Rattus),Rabbit
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name UBA1
Background The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described.
Synonyms: Ubiquitin-like modifier-activating enzyme 1,UBA1,A1S9T, UBE1
Molecular Weight 117849 DA
Gene ID 7317
UniProt P22314, NP_695012.1, NP_003325.2
Research Area Ubiquitin-related antibodies, Signaling, Phospho-specific antibodies, Protein Modifications, Chromatin, Neurology, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment UBA1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Background publications Jin, Li, Gygi et al.: "Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging." in: Nature, Vol. 447, Issue 7148, pp. 1135-8, 2007 (PubMed).

Carbia-Nagashima, Gerez, Perez-Castro et al.: "RSUME, a small RWD-containing protein, enhances SUMO conjugation and stabilizes HIF-1alpha during hypoxia." in: Cell, Vol. 131, Issue 2, pp. 309-23, 2007 (PubMed).

Alternatives for antigen "Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1)", type "Antibodies"
Hosts (27), (3)
Reactivities (28), (9), (6), (3), (3), (1)
Applications (29), (15), (9), (9), (5), (2), (1), (1), (1)
Epitopes (5), (3), (2), (1), (1), (1), (1)
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