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FDFT1 antibody (Farnesyl-Diphosphate Farnesyltransferase 1) (AA 332-361)

Details for Product anti-FDFT1 Antibody No. ABIN658482, Supplier: Log in to see
Antigen
  • DGPT
  • DKFZp459C1712
  • ERG9
  • fdft1
  • FDFT1
  • SQS
  • SS
Epitope
AA 332-361, C-Term
24
16
15
14
10
5
5
5
5
3
1
1
1
1
1
Reactivity
Human
92
18
12
3
1
1
1
1
1
1
Host
Rabbit
88
14
Clonality (Clone)
Polyclonal ()
Conjugate
This FDFT1 antibody is un-conjugated
9
9
6
6
6
6
Application
Western Blotting (WB)
86
61
41
14
11
6
3
3
2
2
Supplier
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Immunogen This FDFT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 332-361 AA from the C-terminal region of human FDFT1.
Clone RB34520
Isotype Ig
Specificity This FDFT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-361 amino acids from the C-terminal region of human FDFT1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name FDFT1 (FDFT1 Antibody Abstract)
Background This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.
Synonyms: Squalene synthase,FDFT1,
Molecular Weight 48115 DA
Gene ID 2222
NCBI Accession NP_004453
UniProt P37268
Research Area Protein Modifications, Cell Structure, Metabolism
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment FDFT1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-FDFT1 antibody (Farnesyl-Diphosphate Farnesyltransferase 1) (AA 332-361) (ABIN658482) FDFT1 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane)...
Western Blotting (WB) image for anti-FDFT1 antibody (Farnesyl-Diphosphate Farnesyltransferase 1) (AA 332-361) (ABIN658482) Western blot analysis of FDFT1 (arrow) using rabbit polyclonal FDFT1 Antibody (C-term...
Background publications Chalasani, Guo, Loomba, Goodarzi, Haritunians, Kwon, Cui, Taylor, Wilson, Cummings, Chen, Rotter,: "Genome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease." in: Gastroenterology, Vol. 139, Issue 5, pp. 1567-76, 1576.e1-6, 2010 (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).