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Details for Product No. ABIN658482

Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) (C-Term), (AA 332-361) antibody

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Antigen
Synonyms SS, SQS, DGPT, ERG9, fdft1, FDFT1, DKFZp459C1712
Epitope
»Alternatives C-Term, AA 332-361
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN658482
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This FDFT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 332-361 AA from the C-terminal region of human FDFT1.
Clone RB34520
Isotype Ig
Specificity This FDFT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-361 amino acids from the C-terminal region of human FDFT1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name FDFT1
Background This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.
Synonyms: Squalene synthase,FDFT1,
Molecular Weight 48115 DA
Gene ID 2222
UniProt NP_004453.3, P37268
Research Area Protein Modifications, Cell Structure, Metabolism
Application Notes Recommend dilutions: WB : 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment FDFT1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Background publications Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Chalasani, Guo, Loomba et al.: "Genome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease." in: Gastroenterology, Vol. 139, Issue 5, pp. 1567-76, 1576.e1-6, 2010 (PubMed).

Alternatives for antigen "Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1)", type "Antibodies"
Hosts (32), (7)
Reactivities (38), (19), (15), (13), (1), (1), (1), (1), (1)
Applications (30), (12), (12), (10), (8), (4), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (6), (3), (2), (2), (2), (1), (1), (1), (1), (1)
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