Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) (C-Term), (AA 332-361) antibody

Details for Product No. ABIN658482
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Antigen
Synonyms FDFT1, DKFZp459C1712, SQS, SS, DGPT, ERG9, fdft1
Epitope
C-Term, AA 332-361
(10), (7), (7), (7), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(53), (17), (16), (13), (1), (1), (1), (1), (1)
Host
Rabbit
(49), (7)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(4), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(47), (29), (17), (16), (10), (4), (3), (3), (2), (1)
Pubmed 2 references available
Quantity 400 µL
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Catalog No. ABIN658482
291.50 $
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Immunogen This FDFT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 332-361 AA from the C-terminal region of human FDFT1.
Clone RB34520
Isotype Ig
Specificity This FDFT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-361 amino acids from the C-terminal region of human FDFT1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name FDFT1
Background This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.
Synonyms: Squalene synthase,FDFT1,
Molecular Weight 48115 DA
Gene ID 2222
NCBI Accession NP_004453
UniProt P37268
Research Area Protein Modifications, Cell Structure, Metabolism
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment FDFT1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) (C-Term), (AA 332-361) antibody FDFT1 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the FDFT1 antibody detected the FDFT1 protein (arrow).
anti-Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) (C-Term), (AA 332-361) antibody (2) Western blot analysis of FDFT1 (arrow) using rabbit polyclonal FDFT1 Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FDFT1 gene.
Background publications Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Chalasani, Guo, Loomba et al.: "Genome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease." in: Gastroenterology, Vol. 139, Issue 5, pp. 1567-76, 1576.e1-6, 2010 (PubMed).

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