Add to Basket Bulk discount
Order hotline:
+1 404 474 4654
+1 888 205 9894 (TF)

Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) (C-Term) antibody

Antigen

Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1)
Synonyms SS, SQS, DGPT, ERG9, MGC93486, FDFT1, MGC134482, fdft1, DKFZp459C1712
Binding Site
Alternatives

C-Term
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), ELISA
2 references available
Certificates ISO 9001:2008
Catalog no. ABIN658482
Quantity 0.1 mg  (0.25 mg/ml)
Price 280.50 $   Plus shipping costs $45.00
Bulk discount
Shipping to
Availability Will be delivered in 2 to 3 Business Days

Additional Information
Application Details Publications Alternatives back to top

Alternative name FDFT1
Gene ID 2222
UniProt NP_004453.3, P37268
Immunogen This FDFT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-361 amino acids from the C-terminal region of human FDFT1.
Isotype Ig
Description Other names: Squalene synthase,FDFT1,
Characteristics Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Specificity This FDFT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-361 amino acids from the C-terminal region of human FDFT1.
Molecular Weight 48115 DA
Comments

Background: This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.

Application Details
Publications Alternatives back to top

Application Notes The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500
Concentration 0.25 mg/ml
Purification Purified
Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage FDFT1 Antibody (C-term) can be refrigerated at 2-8° C for up to 6 months. For long term storage, place the at -20° C.
Research Area Protein Modifications, Cell Structure, Metabolism
Restrictions For Research Use only

Publications
Application Details Alternatives back to top

Product Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Chalasani, Guo, Loomba et al.: "Genome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease." in: Gastroenterology, Vol. 139, Issue 5, pp. 1567-76, 1576.e1-6, 2010 (PubMed).

Alternatives
Application Details Publications back to top

Alternatives for antigen "Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1)", type "Antibodies"
Hosts Rabbit (33), Mouse (2)
Reactivities Human (34), Mouse (Murine) (23), Rat (Rattus) (22), Dog (Canine) (20), Horse (Equine) (18), Rabbit (18), Chicken (2), Cow (Bovine) (2), Cat (Feline) (1), Monkey (1), Pig (Porcine) (1), Zebrafish (1)
Applications Western Blotting (WB) (20), Immunofluorescence (IF) (18), ELISA (15), Immunohistochemistry (IHC) (8), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (8), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Flow Cytometry (FACS) (1), Immunoelectron Microscopy (IEM) (1), Immunoprecipitation (IP) (1)
Conjugates Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1)
Epitopes N-Term (3), Center (1), Internal Region (1)