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Details for Product No. ABIN658513

Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9) (AA 335-363), (Center) antibody

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Antigen
Synonyms CAS-L, CAS2, CASL, CASS2, HEF1, Cas-L, CasL, E230025G09Rik, NEDD9
Epitope
»Alternatives AA 335-363, Center
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 2 references available
Catalog no. ABIN658513
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This NEDD9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 335-363 AA from the Central region of human NEDD9.
Clone RB34579
Isotype Ig
Specificity This NEDD9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 334-363 amino acids from the Central region of human NEDD9.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name NEDD9
Background Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May function in transmitting growth control signals between focal adhesions at the cell periphery and the mitotic spindle in response to adhesion or growth factor signals initiating cell proliferation. May play an important role in integrin beta-1 or B cell antigen receptor (BCR) mediated signaling in B-and T-cells. Integrin beta-1 stimulation leads to recruitment of various proteins including CRK, NCK and SHPTP2 to the tyrosine phosphorylated form.
Synonyms: Enhancer of filamentation 1,NEDD9,CASL, CASS2
Molecular Weight 92861 DA
Gene ID 4739
UniProt NP_006394.1, Q14511, NP_892011.2
Research Area Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications, Cell Cycle
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment NEDD9 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Background publications Lucas, Salimath, Slomiany et al.: "Regulation of invasive behavior by vascular endothelial growth factor is HEF1-dependent." in: Oncogene, Vol. 29, Issue 31, pp. 4449-59, 2010 (PubMed).

Corneveaux, Myers, Allen et al.: "Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals." in: Human molecular genetics, Vol. 19, Issue 16, pp. 3295-301, 2010 (PubMed).

Alternatives for antigen "Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9)", type "Antibodies"
Hosts (24), (18), (5)
Reactivities (42), (22), (20), (15), (12)
Applications (32), (15), (14), (11), (10), (10), (7), (5), (3), (2), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (10), (3), (3), (2), (2), (2), (1), (1)
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