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TAF6 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 80kDa (TAF6) (N-Term), (AA 24-53) antibody

Details for Product No. ABIN658520
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Antigen
Synonyms
CG32211, CG9348, Dmel\\CG32211, SR3-4B, TAF, TAF6, TAF60, TAF60/62, TAFII60, TAFII60(62), TAFII62, TAF[[II]], TAF[[II]]60, TAF[[II]]60/62, TAF[[II]]62, TFIID, TFIID 62, Taf-6, Taf60, Taf62, Taf[[II]]6 ... show more
CG32211, CG9348, Dmel\\CG32211, SR3-4B, TAF, TAF6, TAF60, TAF60/62, TAFII60, TAFII60(62), TAFII62, TAF[[II]], TAF[[II]]60, TAF[[II]]60/62, TAF[[II]]62, TFIID, TFIID 62, Taf-6, Taf60, Taf62, Taf[[II]]60, d60, dTAF6, dTAF62, dTAFII62, dTAF[[II]]262, dTAF[[II]]60, dTAF[[II]]62, dmTAF6, dme-TAFII60, l(3)76BDf, p62, taf6, taf60, wu:fb83e08, wu:fj30b02, zgc:92160, 80kDa, AW549759, TAF(II)80, TAFII70, Taf2e, p80, TAF(II)60, MGC:8964, TAF(II)70, TAF2E, TAFII-70, TAFII-80, TAFII80, TAFII85 show less
Epitope
N-Term, AA 24-53
(11), (7), (3), (2), (2), (2), (1)
Reactivity
Human
(25), (4), (3), (3), (3), (2), (2)
Host
Rabbit
(22), (5)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(25), (8), (7), (3), (3), (3), (2), (2), (2), (1)
Pubmed 2 references available
Quantity 400 µL
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Catalog No. ABIN658520
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Immunogen This TAF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-53 AA from the N-terminal region of human TAF6.
Clone RB34587
Isotype Ig
Specificity This TAF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-53 amino acids from the N-terminal region of human TAF6.
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name TAF6
Background Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds weakly to TBP but strongly to TAF1, the largest subunit of TFIID. Alternative splicing results in multiple transcript variants.
Synonyms: Transcription initiation factor TFIID subunit 6,TAF6,TAF2E, TAFII70
Molecular Weight 72668 DA
Gene ID 6878
UniProt NP_005632.1, NP_647476.1, P49848
Research Area Phospho-specific antibodies, Protein Modifications, Transcription Factors, Signaling, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.3 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment TAF6 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-TAF6 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 80kDa (TAF6) (N-Term), (AA 24-53) antibody TAF6 Antibody (N-term) (ABIN658520) western blot analysis in HepG2 cell line lysates (35 µg/lane). This demonstrates the TAF6 antibody detected the TAF6 protein (arrow).
Background publications Beausoleil, Jedrychowski, Schwartz et al.: "Large-scale characterization of HeLa cell nuclear phosphoproteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, 2004 (PubMed).

Frontini, Soutoglou, Argentini et al.: "TAF9b (formerly TAF9L) is a bona fide TAF that has unique and overlapping roles with TAF9." in: Molecular and cellular biology, Vol. 25, Issue 11, pp. 4638-49, 2005 (PubMed).

Validation Images
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