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Details for Product No. ABIN658520

TAF6 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 80kDa (TAF6) (N-Term), (AA 24-53) antibody

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MGC:8964, TAF(II)70, TAF(II)80, TAF2E, TAFII-70, TAFII-80, TAFII70, TAFII80, TAFII85, 80kDa, AW549759, Taf2e, p80, wu:fb83e08, wu:fj30b02, zgc:92160, TAF(II)60, CG32211, CG9348, Dmel\\CG32211, SR3-4B, ... show more
»Alternatives N-Term, AA 24-53
»Alternatives Human
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
»Alternatives Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN658520
Quantity 400 µL
291.50 $   Plus shipping costs $45.00
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Immunogen This TAF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-53 AA from the N-terminal region of human TAF6.
Clone RB34587
Isotype Ig
Specificity This TAF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-53 amino acids from the N-terminal region of human TAF6.
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name TAF6
Background Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds weakly to TBP but strongly to TAF1, the largest subunit of TFIID. Alternative splicing results in multiple transcript variants.
Synonyms: Transcription initiation factor TFIID subunit 6,TAF6,TAF2E, TAFII70
Molecular Weight 72668 DA
Gene ID 6878
UniProt NP_005632.1, NP_647476.1, P49848
Research Area Phospho-specific antibodies, Protein Modifications, Transcription Factors, Signaling, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.3 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment TAF6 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Background publications Beausoleil, Jedrychowski, Schwartz et al.: "Large-scale characterization of HeLa cell nuclear phosphoproteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, 2004 (PubMed).

Frontini, Soutoglou, Argentini et al.: "TAF9b (formerly TAF9L) is a bona fide TAF that has unique and overlapping roles with TAF9." in: Molecular and cellular biology, Vol. 25, Issue 11, pp. 4638-49, 2005 (PubMed).

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