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Epidermal Growth Factor Receptor (EGFR) (C-Term,Ser1081) antibody

Antigen

Epidermal Growth Factor Receptor (EGFR)
Synonyms
ERBB, HER1, mENA, ERBB1, PIG61, Wa5, wa2, Erbb, Errp, wa-2, AI552599, 9030024J15Rik, ErbB-1, C-erb, D-EGFR, D-Egf, DEGFR, DER, DER flb, DER/EGFR, DER/faint little ball, DER/top, DER/torpedo, DmHD-33,  ... show more
Binding Site
Alternatives

C-Term,Ser1081
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), ELISA
2 references available
Certificates ISO 9001:2008
Catalog no. ABIN658590
Quantity 0.1 mg  (0.25 mg/ml)
Price 280.50 $   Plus shipping costs $45.00
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anti-Epidermal Growth Factor Receptor (EGFR) (C-Term,Ser1081) antibody

Additional Information
Application Details Publications Images Alternatives back to top

Alternative name EGFR
Isotype Ig
Description Other names: Epidermal growth factor receptor,EGFR,ERBB1
Characteristics Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Specificity This EGFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human EGFR.
Comments

Background: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.
Synonyms ERBB, HER1, mENA, ERBB1, PIG61, Wa5, wa2, Erbb, Errp, wa-2, AI552599, 9030024J15Rik, ErbB-1, C-erb, D-EGFR, D-Egf, DEGFR, DER, DER flb, DER/EGFR, DER/faint little ball, DER/top, DER/torpedo, DmHD-33, EFG-R, EGF-R, EGFR, EK2-6, Egf, El, Elp, Elp-1, Elp-B1, Elp-B1RB1, HD-33, Torpedo/DER, Torpedo/Egfr, c-erbB, d-egf-r, dEGFR1, flb, l(2)05351, l(2)09261, l(2)57DEFa, l(2)57EFa, l(2)57Ea, pnt, top, top/DER, top/flb, DmelCG10079, CG10079, egfr, EGFR12, EGFR15, egfr1, Erbb2

Application Details
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Concentration 0.25 mg/ml
Purification Purified
Research Area Ubiquitin-related antibodies, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure, Cancer, Signaling, Chromatin
Restrictions For Research Use only

Publications
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Product Abdallah, Keum, El-Shewy et al.: "Plasma kallikrein promotes epidermal growth factor receptor transactivation and signaling in vascular smooth muscle through direct activation of protease-activated receptors." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 35206-15, 2010 (PubMed).

Aguirre, Rubio, Gallo: "Notch and EGFR pathway interaction regulates neural stem cell number and self-renewal." in: Nature, Vol. 467, Issue 7313, pp. 323-7, 2010 (PubMed).

Alternatives
Application Details Publications Images back to top

Alternatives for antigen "Epidermal Growth Factor Receptor (EGFR)", type "Antibodies"
Hosts Rabbit (880), Mouse (202), Rat (18), Sheep (9), Goat (3), Mouse (Murine) (1)
Reactivities Human (1096), Mouse (Murine) (596), Rat (Rattus) (580), Pig (Porcine) (218), Dog (Canine) (197), Horse (Equine) (182), Cow (Bovine) (163), Chicken (93), Sheep (Ovine) (36), Rabbit (19), Cat (Feline) (1)
Applications Western Blotting (WB) (555), Immunofluorescence (IF) (429), ELISA (352), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (231), Immunoprecipitation (IP) (175), Immunohistochemistry (IHC) (133), Flow Cytometry (FACS) (92), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (74), Immunocytochemistry (ICC) (57), Immunohistochemistry (Frozen Sections) (IHC (fro)) (32), Immunoelectron Microscopy (IEM) (25), Blocking Antibody (Inhibition) (18), Dot Blot (Dot) (16), Immunohistochemistry (Fixed) (IHC (fx)) (15), Functional Studies (Func) (3), Cellular Assay (CA) (2), Enzyme Immunoassay (EIA) (2), Immunoassay (IA) (2), Immunostaining (ISt) (2), Blocking Antibody (Inhibition) (1), Cell-ELISA (cELISA) (1), Electrophoretic Mobility-Shift Assay (EMSA) (1), Neutralization (Neut) (1)
Conjugates Biotin (61), FITC (30), PE (26), Alexa Fluor 488 (25), Alexa Fluor 350 (24), Alexa Fluor 555 (24), Alexa Fluor 647 (24), Cy3 (24), Cy5 (24), Cy5.5 (24), Cy7 (24), Gold (24), HRP (24), PE,Cy3 (23), PE,Cy5 (23), PE,Cy5.5 (23), PE,Cy7 (23), RPE (2), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1)
Epitopes C-Term (87), pTyr1197 (39), pTyr869 (38), pTyr1092 (37), pTyr1110 (35), pSer1070 (33), pThr678 (33), pThr693 (30), Extracellular Domain (26), pTyr1016 (23), pSer1026 (22), pSer695 (22), pTyr1068 (22), pSer1166 (21), pSer1190 (21), pSer768 (21), pTyr1125 (21), pTyr845 (21), pTyr998 (21), pTyr1045 (20), pSer1142 (18), pSer991 (18), pTyr1172 (18), pTyr1148 (13), pTyr1173 (12), Internal Region (8), N-Term (6), Tyr1197 (6), pSer695,Internal Region (6), pTyr1069 (6), pTyr1138 (5), AA 1189-1199 (4), Ser1070 (4), Tyr1092 (4), Tyr1110 (4), Tyr1172 (4), Tyr869 (4), AA 1165-1186 (3), AA 985-996 (3), Thr693 (3), Tyr1016 (3), pSer1071 (3), pTyr1069,C-Term (3), pTyr992 (3), AA 1140-1160 (2), AA 424-605 (2), AA 960-980 (2), Extracellular, Ligand Binding Domain (2), Extracellular, non Ligand Binding Domain (2), Ligand Binding Domain (2), Ser1071 (2), Ser695 (2), Ser991 (2), Thr678 (2), Tyr1068 (2), Tyr1125 (2), Tyr978 (2), Tyr998 (2), pSer1047 (2), pThr654 (2), AA 1165-1185 (1), AA 1166-1180 (1), AA 1189-1199,pTyr1197 (1), C-Term, Ser1026 (1), C-Term,AA 1010-1029 (1), C-Term,AA 1163-1191 (1), Extracellular,Non-Ligand binding Domain (1), Ligand binding Domain (1), Middle Region (1), N-Term,AA 259-287 (1), Ser1026 (1), pSer1045 (1), pSer1070, pSer1071 (1), pThr637 (1), pThr693,pThr678 (1), pTyr1086 (1)