Minichromosome Maintenance Complex Component 6 (MCM6) (AA 80-109), (N-Term) antibody

Details for Product No. ABIN658615, Supplier: Log in to see
Antigen
  • CG4039
  • DmMCM6
  • DmeMCM6
  • Dmel\\CG4039
  • MCM6
  • McM6
  • fs(1)K1214
  • mcm6
  • MCG40308
  • Mis5
  • P105MCM
  • Mcmd6
  • mis5
  • mmcm6
  • ASP-l1
  • D1Wsu22e
  • Minichromosome maintenance 6
  • DNA replication licensing factor MCM6
  • minichromosome maintenance complex component 6
  • minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)
  • Protein MCM-6
  • Mcm6
  • TP02_0113
  • PVX_114735
  • CMU_027970
  • MCM6
  • mcm6
  • mcm-6
Alternatives
anti-Human Minichromosome Maintenance Complex Component 6 antibody for Western Blotting
Epitope
AA 80-109, N-Term
17
15
10
5
5
4
3
3
2
2
2
1
1
1
1
Reactivity
Human
89
33
21
17
12
12
10
8
4
2
1
1
1
1
Host
Rabbit
80
7
4
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
83
46
29
26
17
6
5
3
2
2
1
1
1
1
1
Options
Supplier
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Immunogen This MCM6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 80-109 AA from the N-terminal region of human MCM6.
Clone RB34942
Isotype Ig
Specificity This MCM6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-109 amino acids from the N-terminal region of human MCM6.
Predicted Reactivity Cow (Bovine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name MCM6 (MCM6 Antibody Abstract)
Background The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.
Synonyms: DNA replication licensing factor MCM6,MCM6,
Research Area Signaling, Phospho-specific antibodies, Protein Modifications, Transcription Factors, Chromatin, Cell Structure
Pathways DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
Western Blotting (WB) image for anti-Minichromosome Maintenance Complex Component 6 (MCM6) (AA 80-109), (N-Term) antibody (ABIN658615) MCM6 Antibody (N-term) (ABIN658615) western blot analysis in 293 cell line lysates (3...
Background publications Wei, Liu, Wu, Xu, Zhou, Liang, Zhu: "Characterization and structure determination of the Cdt1 binding domain of human minichromosome maintenance (Mcm) 6." in: The Journal of biological chemistry, Vol. 285, Issue 17, pp. 12469-73, 2010 (PubMed).

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