Multiple Inositol-Polyphosphate Phosphatase 1 (MINPP1) (C-Term) antibody

Antigen: Multiple Inositol-Polyphosphate Phosphatase 1 (MINPP1)

Synonyms: MIPP, HIPER1, MINPP2, DKFZp564L2016, AA408516, minpp1, MGC56080, zgc:56080, zgc:76991, MGC134477, DKFZp469H164

Binding Site: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN658617

Additional Information

Alternative name: MINPP1

Isotype: Ig

Description: Other names: Multiple inositol polyphosphate phosphatase 1,MINPP1,MIPP

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This MINPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 369-348 amino acids from the C-terminal region of human MINPP1.

Comments:

Background: This gene encodes multiple inositol polyphosphate phosphatase, an enzyme that removes 3-phosphate from inositol phosphate substrates. It is the only enzyme known to hydrolzye inositol pentakisphosphate and inositol hexakisphosphate. This enzyme also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate, an activity formerly thought to be exclusive to 2,3-BPG synthase/2-phosphatase (BPGM) in the Rapoport-Luebering shunt of the glycolytic pathway.

Application Details

Concentration: 0.25 mg/ml

Purification: Purified

Research Area: Cell Signaling, Protein Modifications, Metabolism, Cell Structure

Restrictions: For Research Use only

Images

MINPP1 Antibody (C-term) (ABIN658617) western blot analysis in NCI-H460 cell line lysates (35ug/lane). This demonstrates the MINPP1 antibody detected the MINPP1 protein (arrow).

Publications

Product: Grupe, Li, Rowland et al.: "A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease." in: American journal of human genetics, Vol. 78, Issue 1, pp. 78-88, 2005 (PubMed).

Lamesch, Li, Milstein et al.: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, 2007 (PubMed).