V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) (N-Term), (AA 22-49) antibody

Details for Product No. ABIN658621
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

 
Antigen
Synonyms
AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA, pkb, xAct, akt-1, v-akt, v-akt1, Akt, AKT1, ATAKT1, F18A8.2, F18A8_2, K+ transporter 1, POTASSIUM TRANSPORTER, AKT/PKB, Akt/PKB, Akt1, CG4006, D-Akt,  ... show more
AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA, pkb, xAct, akt-1, v-akt, v-akt1, Akt, AKT1, ATAKT1, F18A8.2, F18A8_2, K+ transporter 1, POTASSIUM TRANSPORTER, AKT/PKB, Akt/PKB, Akt1, CG4006, D-Akt, DAKT1, DAKT1/PKB, DAkt, DAkt1, DPKB, DRAC-PK, DRAC-PK66, DRAC-PK85, Dakt, Dakt1, Dmel\\CG4006, Dpkb, PKB/AKT, PKB/Akt, PKB/dAKT, RacPK, akt, akt1, dAKT, dAKT/dPKB, dAKT1, dAkt, dAkt/PKB, dAkt1, dPKB, dakt, dakt1, l(3)04226, l(3)89Bq, p-Akt, pAkt show less
Epitope
N-Term, AA 22-49
(129), (88), (54), (50), (48), (32), (32), (29), (28), (17), (16), (16), (11), (9), (9), (8), (5), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine)
(838), (536), (514), (167), (153), (115), (94), (21), (18), (4), (3), (1), (1), (1), (1)
Host
Rabbit
(698), (144), (7), (5), (4), (3)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(20), (14), (13), (13), (13), (13), (13), (13), (13), (13), (13), (9), (7), (7), (7), (7), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(637), (361), (239), (161), (139), (130), (124), (66), (44), (17), (11), (5), (5), (3), (3), (2), (1), (1), (1), (1), (1), (1)
Pubmed 3 references available
Catalog no. ABIN658621
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
Options
Shipping to United States (Change)
Availability Will be delivered in 2 to 3 Business Days

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This Mouse Akt1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-49 AA from the N-terminal region of mouse Akt1.
Clone RB34732
Isotype Ig
Specificity This Mouse Akt1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-49 amino acids from the N-terminal region of Mouse Akt1.
Predicted Reactivity Human
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name Akt1
Background This gene encodes the founding member of the Akt serine-threonine protein kinase gene family that also includes Akt2 and Akt3. This kinase is a major downstream effector of the phosphatidylinositol 3-kinase (PI3K) pathway that mediates the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), insulin and insulin-like growth factor I (IGF-I). It is activated through recruitment to cellular membranes by PI3K lipid products and by phosphorylation by 3-phosphoinositide dependent kinase-1. It then further phosphorylates different downstream proteins in response to various extracellular signals and thus plays a pivotal role in mediating a variety of cellular processes, such as glucose metabolism, glycogen biosynthesis, protein synthesis and turn over, inflammatory response, cell survival (anti-apoptosis) and development. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Synonyms: RAC-alpha serine/threonine-protein kinase,Akt1,Akt, Rac
Research Area Translation Factors, Protein Modifications, Signaling, Neurology, Cell Structure, Ubiquitin-related antibodies, Apoptosis/Necrosis, Phospho-specific antibodies, Cell Signaling, Chromatin, Metabolism
Application Notes WB = 1:1000, IHC = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Supplier Images
anti-V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) (N-Term), (AA 22-49) antibody Mouse Akt1 Antibody (N-term) (ABIN658621) western blot analysis in mouse heart tissue lysates (35 µg/lane). This demonstrates the Akt1 antibody detected the Akt1 protein (arrow).
Background publications Zhou, Chang, Zhang et al.: "Akt/Protein kinase B is required for lymphatic network formation, remodeling, and valve development." in: The American journal of pathology, Vol. 177, Issue 4, pp. 2124-33, 2010 (PubMed).

Chang, Zhang, Feng et al.: "Deletion of Akt1 causes heart defects and abnormal cardiomyocyte proliferation." in: Developmental biology, Vol. 347, Issue 2, pp. 384-91, 2010 (PubMed).

Sun, Xie, Yang et al.: "Endocannabinoid signaling directs differentiation of trophoblast cell lineages and placentation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 39, pp. 16887-92, 2010 (PubMed).

Hosts (698), (144), (7), (5), (4), (3)
Reactivities (838), (536), (514), (167), (153), (115), (94), (21), (18), (4), (3), (1), (1), (1), (1)
Applications (637), (361), (239), (161), (139), (130), (124), (66), (44), (17), (11), (5), (5), (3), (3), (2), (1), (1), (1), (1), (1), (1)
Conjugates (20), (14), (13), (13), (13), (13), (13), (13), (13), (13), (13), (9), (7), (7), (7), (7), (1), (1), (1), (1), (1), (1)
Epitopes (129), (88), (54), (50), (48), (32), (32), (29), (28), (17), (16), (16), (11), (9), (9), (8), (5), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
back to top