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Details for Product No. ABIN658633

Death-Associated Protein Kinase 3 (DAPK3) (AA 255-282), (Center) antibody

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Synonyms ZIP, ZIPK, dlk, Dapkl, DAPK3, dapk3, wu:fc25b08, si:dkey-57k2.5, MGC114871
»Alternatives AA 255-282, Center
»Alternatives Mouse (Murine)
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
»Alternatives Un-conjugated
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 5 references available
Catalog no. ABIN658633
Quantity 400 µL
291.50 $   Plus shipping costs $45.00
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Immunogen This Mouse Dapk3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 255-282 AA from the Central region of mouse Dapk3.
Clone RB34753
Isotype Ig
Specificity This Mouse Dapk3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 254-282 amino acids from the Central region of Mouse Dapk3.
Predicted Reactivity Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name Dapk3
Background Serine/threonine kinase which acts as a positive regulator of apoptosis. Phosphorylates histone H3 on 'Thr-11' at centromeres during mitosis. Regulates myosin light chain phosphatase through phosphorylation of MYPT1 thereby regulating the assembly of the actin cytoskeleton, cell migration, invasiveness of tumor cells, smooth muscle contraction and neurite outgrowth. Involved in the formation of promyelocytic leukemia protein nuclear body (PML-NB), one of many subnuclear domains in the eukaryotic cell nucleus, and which is involved in oncogenesis and viral infection (By similarity).
Synonyms: Death-associated protein kinase 3,Dapk3,Zipk
Research Area Ubiquitin-related antibodies, Apoptosis/Necrosis, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Signaling, Chromatin, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Background publications Sato, Kawai, Sugiyama et al.: "Physical and functional interactions between STAT3 and ZIP kinase." in: International immunology, Vol. 17, Issue 12, pp. 1543-52, 2005 (PubMed).

Shoval, Pietrokovski, Kimchi: "ZIPK: a unique case of murine-specific divergence of a conserved vertebrate gene." in: PLoS genetics, Vol. 3, Issue 10, pp. 1884-93, 2007 (PubMed).

Wooldridge, Fortner, Lontay et al.: "Deletion of the protein kinase A/protein kinase G target SMTNL1 promotes an exercise-adapted phenotype in vascular smooth muscle." in: The Journal of biological chemistry, Vol. 283, Issue 17, pp. 11850-9, 2008 (PubMed).

Ohbayashi, Okada, Kawakami et al.: "Physical and functional interactions between ZIP kinase and UbcH5." in: Biochemical and biophysical research communications, Vol. 372, Issue 4, pp. 708-12, 2008 (PubMed).

Chang, Chen, Gerard et al.: "Cardiac myosin is a substrate for zipper-interacting protein kinase (ZIPK)." in: The Journal of biological chemistry, Vol. 285, Issue 8, pp. 5122-6, 2010 (PubMed).

Alternatives for antigen "Death-Associated Protein Kinase 3 (DAPK3)", type "Antibodies"
Hosts (69), (1), (1)
Reactivities (69), (41), (38), (13), (12), (12)
Applications (60), (29), (14), (13), (10), (10), (10), (1), (1), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (8), (5), (4), (4), (2), (2), (1), (1), (1), (1), (1)