DAPK3 antibody (Death-Associated Protein Kinase 3) (AA 255-282)

Details for Product anti-DAPK3 Antibody No. ABIN658633, Supplier: Log in to see
Antigen
  • DAPK3
  • dapk3
  • wu:fc25b08
  • si:dkey-57k2.5
  • MGC114871
  • ZIP
  • ZIPK
  • dlk
  • Dapkl
  • death-associated protein kinase 3
  • Death-associated protein kinase 3
  • DAPK3
  • dapk3
  • Dapk3
Epitope
AA 255-282, Center
15
14
11
8
6
5
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine)
83
47
28
2
1
1
1
Host
Rabbit
79
22
Clonality (Clone)
Polyclonal ()
Conjugate
This DAPK3 antibody is un-conjugated
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
94
56
48
19
15
14
11
4
2
1
1
1
1
Options
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Immunogen This Mouse Dapk3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 255-282 AA from the Central region of mouse Dapk3.
Clone RB34753
Isotype Ig
Specificity This Mouse Dapk3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 254-282 amino acids from the Central region of Mouse Dapk3.
Predicted Reactivity Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name Dapk3 (DAPK3 Antibody Abstract)
Background Serine/threonine kinase which acts as a positive regulator of apoptosis. Phosphorylates histone H3 on 'Thr-11' at centromeres during mitosis. Regulates myosin light chain phosphatase through phosphorylation of MYPT1 thereby regulating the assembly of the actin cytoskeleton, cell migration, invasiveness of tumor cells, smooth muscle contraction and neurite outgrowth. Involved in the formation of promyelocytic leukemia protein nuclear body (PML-NB), one of many subnuclear domains in the eukaryotic cell nucleus, and which is involved in oncogenesis and viral infection (By similarity).
Synonyms: Death-associated protein kinase 3,Dapk3,Zipk
Research Area Ubiquitin-related antibodies, Apoptosis/Necrosis, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Signaling, Chromatin, Cell Structure
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
Western Blotting (WB) image for anti-DAPK3 antibody (Death-Associated Protein Kinase 3) (AA 255-282) (ABIN658633) Mouse Dapk3 Antibody (Center) (ABIN658633) western blot analysis in mouse testis tiss...
Background publications Chang, Chen, Gerard, Kamm, Stull: "Cardiac myosin is a substrate for zipper-interacting protein kinase (ZIPK)." in: The Journal of biological chemistry, Vol. 285, Issue 8, pp. 5122-6, 2010 (PubMed).

Ohbayashi, Okada, Kawakami, Togi, Sato, Ikeda, Kamitani, Muromoto, Sekine, Kawai, Akira, Matsuda: "Physical and functional interactions between ZIP kinase and UbcH5." in: Biochemical and biophysical research communications, Vol. 372, Issue 4, pp. 708-12, 2008 (PubMed).

Wooldridge, Fortner, Lontay, Akimoto, Neppl, Facemire, Datto, Kwon, McCook, Li, Wang, Thresher, Miller, Perriard, Gavin, Hickner, Coffman, Somlyo, Yan, Haystead: "Deletion of the protein kinase A/protein kinase G target SMTNL1 promotes an exercise-adapted phenotype in vascular smooth muscle." in: The Journal of biological chemistry, Vol. 283, Issue 17, pp. 11850-9, 2008 (PubMed).

Shoval, Pietrokovski, Kimchi: "ZIPK: a unique case of murine-specific divergence of a conserved vertebrate gene." in: PLoS genetics, Vol. 3, Issue 10, pp. 1884-93, 2007 (PubMed).

Sato, Kawai, Sugiyama, Muromoto, Imoto, Sekine, Ishida, Akira, Matsuda: "Physical and functional interactions between STAT3 and ZIP kinase." in: International immunology, Vol. 17, Issue 12, pp. 1543-52, 2005 (PubMed).