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Details for Product No. ABIN658691

Transcriptional Adaptor 3 (TADA3) (C-Term), (AA 386-414) antibody

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Synonyms ADA3, NGG1, STAF54, TADA3L, hADA3, Tada3l, 1110004B19Rik, AI987856, fa03f04, tada3, wu:fa03f04, zgc:63596
»Alternatives C-Term, AA 386-414
»Alternatives Human
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
»Alternatives Un-conjugated
»Alternatives Western Blotting (WB), Immunofluorescence (IF)
Pubmed 2 references available
Catalog no. ABIN658691
Quantity 400 µL
291.50 $   Plus shipping costs $45.00
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Immunogen This TADA3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 386-414 AA from the C-terminal region of human TADA3L.
Clone RB35022
Isotype Ig
Specificity This TADA3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 385-414 amino acids from the C-terminal region of human TADA3L.
Predicted Reactivity Cow (Bovine),Mouse (Murine),Rat (Rattus),Xenopus laevis,Zebrafish
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name TADA3L
Background Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq].
Synonyms: Transcriptional adapter 3,TADA3,ADA3, TADA3L
Research Area Signaling, Protein Modifications, Transcription Factors, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IF : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Background publications Wang, Faiola, Xu et al.: "Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein." in: The Journal of biological chemistry, Vol. 283, Issue 49, pp. 33808-15, 2008 (PubMed).

Hu, Ye, Lu et al.: "HPV16 E6-induced and E6AP-dependent inhibition of the transcriptional coactivator hADA3 in human cervical carcinoma cells." in: Cancer investigation, Vol. 27, Issue 3, pp. 298-306, 2009 (PubMed).

Alternatives for antigen "Transcriptional Adaptor 3 (TADA3)", type "Antibodies"
Hosts (19), (7)
Reactivities (26), (7), (7), (4), (4), (4), (4), (4)
Applications (25), (13), (6), (3), (3), (2)
Conjugates (1), (1), (1)
Epitopes (5), (2), (2), (2), (2), (2), (1), (1)