Ubiquitin Specific Peptidase 30 (Usp30) (N-Term) antibody

Antigen: Ubiquitin Specific Peptidase 30 (Usp30)

Synonyms: FLJ40511, MGC10702, AI851327, D5Ertd483e, 6330590F17Rik, si:dkey-72n1.2

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN658703

Additional Information

Alternative name: USP30

Isotype: Ig

Description: Other names: Ubiquitin carboxyl-terminal hydrolase 30,USP30,

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This USP30 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 155-185 amino acids from the N-terminal region of human USP30.

Comments:

Background: USP30, a member of the ubiquitin-specific protease family (see USP1, MIM 603478), is a novel mitochondrial deubiquitinating (DUB) enzyme (Nakamura and Hirose, 2008 [PubMed 18287522]).

Application Details

Concentration: 0.25 mg/ml

Purification: Purified

Research Area: Cell Structure, Metabolism

Restrictions: For Research Use only

Images

USP30 Antibody (N-term) (ABIN658703) western blot analysis in A549 cell line lysates (35ug/lane). This demonstrates the USP30 antibody detected the USP30 protein (arrow).

Publications

Product: Puente, Sánchez, Overall et al.: "Human and mouse proteases: a comparative genomic approach." in: Nature reviews. Genetics, Vol. 4, Issue 7, pp. 544-58, 2003 (PubMed).

Quesada, Díaz-Perales, Gutiérrez-Fernández et al.: "Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases." in: Biochemical and biophysical research communications, Vol. 314, Issue 1, pp. 54-62, 2004 (PubMed).

Nakamura, Hirose: "Regulation of mitochondrial morphology by USP30, a deubiquitinating enzyme present in the mitochondrial outer membrane." in: Molecular biology of the cell, Vol. 19, Issue 5, pp. 1903-11, 2008 (PubMed).