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Details for Product No. ABIN658724

Cleavage and Polyadenylation Specific Factor 3, 73kDa (CPSF3) (AA 192-221), (Center) antibody

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Antigen
Synonyms CPSF-73, CPSF73, si:dkey-81b15.1, wu:fc32f10, zgc:101655, CPSF3
Epitope
»Alternatives AA 192-221, Center
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Application
»Alternatives Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN658724
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This CPSF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-221 AA from the Central region of human CPSF3.
Clone RB34115
Isotype Ig
Specificity This CPSF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-221 amino acids from the Central region of human CPSF3.
Predicted Reactivity Cow (Bovine),Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name CPSF3
Background Most eukaryotic mRNA precursors (pre-mRNAs) undergo extensive maturational processing, including cleavage and polyadenylation at the 3-prime end. CPSF3 encodes the 73-kD subunit of the cleavage and polyadenylation specificity factor (CPSF) and is the pre-mRNA 3-prime-end-processing endonuclease (Mandel et al., 2006 [PubMed 17128255]).
Synonyms: Cleavage and polyadenylation specificity factor subunit 3,CPSF3,CPSF73
Research Area Ubiquitin-related antibodies, Translation Factors, Phospho-specific antibodies, Protein Modifications, Transcription Factors, Signaling, Chromatin, Metabolism, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Background publications Zhu, Yu, Shi et al.: "CSR1 induces cell death through inactivation of CPSF3." in: Oncogene, Vol. 28, Issue 1, pp. 41-51, 2009 (PubMed).

Rozenblatt-Rosen, Nagaike, Francis et al.: "The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 3, pp. 755-60, 2009 (PubMed).

Alternatives for antigen "Cleavage and Polyadenylation Specific Factor 3, 73kDa (CPSF3)", type "Antibodies"
Hosts (20), (9)
Reactivities (25), (5), (5), (2), (2), (2), (1), (1)
Applications (26), (10), (4), (4), (3), (2), (1), (1)
Epitopes (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
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