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CPSF3 antibody (Cleavage and Polyadenylation Specific Factor 3, 73kDa) (AA 192-221)

Details for Product anti-CPSF3 Antibody No. ABIN658724, Supplier: Log in to see
Antigen
  • CPSF-73
  • CPSF3
  • CPSF73
  • si:dkey-81b15.1
  • wu:fc32f10
  • zgc:101655
Epitope
AA 192-221, Center
16
13
10
10
4
4
3
3
3
3
3
2
1
1
1
Reactivity
Human
59
7
6
4
2
2
1
1
Host
Rabbit
41
18
Clonality (Clone)
Polyclonal ()
Conjugate
This CPSF3 antibody is un-conjugated
3
3
3
3
3
3
Application
Western Blotting (WB)
55
32
9
7
6
5
3
1
1
Supplier
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Immunogen This CPSF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-221 AA from the Central region of human CPSF3.
Clone RB34115
Isotype Ig
Specificity This CPSF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-221 amino acids from the Central region of human CPSF3.
Predicted Reactivity Cow (Bovine),Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name CPSF3 (CPSF3 Antibody Abstract)
Background Most eukaryotic mRNA precursors (pre-mRNAs) undergo extensive maturational processing, including cleavage and polyadenylation at the 3-prime end. CPSF3 encodes the 73-kD subunit of the cleavage and polyadenylation specificity factor (CPSF) and is the pre-mRNA 3-prime-end-processing endonuclease (Mandel et al., 2006 [PubMed 17128255]).
Synonyms: Cleavage and polyadenylation specificity factor subunit 3,CPSF3,CPSF73
Research Area Ubiquitin-related antibodies, Translation Factors, Phospho-specific antibodies, Protein Modifications, Transcription Factors, Signaling, Chromatin, Metabolism, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
Western Blotting (WB) image for anti-CPSF3 antibody (Cleavage and Polyadenylation Specific Factor 3, 73kDa) (AA 192-221) (ABIN658724) CPSF3 Antibody (Center) (ABIN658724) western blot analysis in A375 cell line lysates ...
Background publications Rozenblatt-Rosen, Nagaike, Francis, Kaneko, Glatt, Hughes, LaFramboise, Manley, Meyerson: "The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 3, pp. 755-60, 2009 (PubMed).

Zhu, Yu, Shi, Nelson, Luo: "CSR1 induces cell death through inactivation of CPSF3." in: Oncogene, Vol. 28, Issue 1, pp. 41-51, 2009 (PubMed).